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日本宣布紧急状态前后糖尿病患者生活方式改变对血糖控制影响的研究

Study on the effects of changes in lifestyle of patients with diabetes on glycaemic control before and after the declaration of the state of emergency in Japan.

作者信息

Masuda Mio, Tomonaga Osamu

机构信息

Berry Clinic, 4-14-10 Ainokawa, Ichikawa, Chiba 299-3235 Japan.

Diabetes and Lifestyle Center, Tomonaga Clinic, Shinyon Curumu Building 9F, 4-2-23 Shinjuku, Shinjuku-ku, Tokyo, 160-0022 Japan.

出版信息

Diabetol Int. 2021 Apr 20;13(1):66-74. doi: 10.1007/s13340-021-00505-6. eCollection 2022 Jan.

DOI:10.1007/s13340-021-00505-6
PMID:33898154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8056092/
Abstract

OBJECTIVE

To investigate the actual conditions of changes in lifestyle and treatment status of patients with diabetes before and after the declaration of the state of emergency issued in response to the novel coronavirus.

METHODS

This study was a collaborative study in two diabetes clinics. A total of 1000 subjects responded to the questionnaire. In addition, data on HbA1c and body weight before and after the declaration of the state of emergency were collected.

RESULTS

HbA1c levels significantly decreased from 7.28 ± 0.97% before the declaration of the state of emergency to 7.07 ± 0.86% after the declaration ( < 0.001). A significant decrease in HbA1c levels was also noted in both T2DM and T1DM. A factorial analysis of the change in HbA1c levels found that a high HbA1c level before the declaration was the most influential factor that made the HbA1c level more likely to decrease, with such factors including a good amount of exercise. A positive correlation with change in body weight was noted. Factors that made the HbA1c level less likely to decrease included stress felt about school closures for children, increased opportunities to eat out, increased food consumption, and refraining from exercise to avoid the "Three Cs" (crowded places, close-contact settings, and confined and enclosed spaces).

CONCLUSION

In the absence of serious economic stagnation or completely disrupted distribution, patients are allowed time to do what they like and can probably improve their glycaemic control status if they see this time as an opportunity.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s13340-021-00505-6.

摘要

目的

调查在针对新型冠状病毒发布紧急状态声明前后糖尿病患者生活方式变化及治疗状况的实际情况。

方法

本研究是在两家糖尿病诊所开展的合作研究。共有1000名受试者回答了问卷。此外,收集了紧急状态声明前后的糖化血红蛋白(HbA1c)和体重数据。

结果

糖化血红蛋白水平从紧急状态声明前的7.28±0.97%显著降至声明后的7.07±0.86%(<0.001)。2型糖尿病(T2DM)和1型糖尿病(T1DM)患者的糖化血红蛋白水平均显著下降。对糖化血红蛋白水平变化的因子分析发现,声明前较高的糖化血红蛋白水平是使其更有可能下降的最具影响力因素,其中包括大量运动等因素。体重变化与之呈正相关。使糖化血红蛋白水平不太可能下降的因素包括对子女学校停课的压力感、外出就餐机会增加、食物摄入量增加以及为避免“三密”(拥挤场所、密闭空间和密闭环境)而避免运动。

结论

在没有严重经济停滞或供应完全中断的情况下,如果患者将这段时间视为一个机会,他们有时间做自己喜欢的事情,血糖控制状况可能会得到改善。

补充信息

在线版本包含可在10.1007/s13340-021-00505-6获取的补充材料。