Hosomi Yukako, Munekawa Chihiro, Hashimoto Yoshitaka, Okamura Takuro, Takahashi Fuyuko, Kawano Rena, Nakajima Hanako, Majima Saori, Senmaru Takafumi, Nakanishi Naoko, Ushigome Emi, Hamaguchi Masahide, Yamazaki Masahiro, Fukui Michiaki
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566 Japan.
Diabetol Int. 2021 Apr 19;13(1):85-90. doi: 10.1007/s13340-021-00507-4. eCollection 2022 Jan.
To investigate the acute effects of coronavirus disease (COVID-19) on lifestyle and metabolic parameters in patients with type 1 diabetes (T1D).
This retrospective cohort study included 34 patients who were admitted to our hospital from April 16 to May 1, 2020. Data on stress levels, sleep duration, exercise, total diet, snacks, and prepared food intake were obtained from the questionnaires. Changes in the values of hemoglobin A1c (HbA1c) and body weight from 3 months before the administration of the questionnaire to the time the study questionnaire was administered (pandemic year), and those from 15 months before to 12 months before the administration of the questionnaire (pre-pandemic year) were evaluated.
Increased stress levels and decreased exercise volumes were observed in approximately 60% and 50% of participants during the COVID-19 pandemic, respectively. Decreased sleep duration was associated with changes in the body weight for 3 months during pandemic year ( = - 0.40, = 0.043). Furthermore, compared with changes in HbA1c for 3 months during pre-pandemic year, changes in HbA1c during the pandemic year were worse (0.12% [0.33] % during pandemic year vs. - 0.09 [0.39] % during pre-pandemic year, = 0.027).
Many patients experienced stress and exercised less due to the COVID-19 pandemic. Glycemic control in patients with T1D was worse than that in the previous year. Since the pandemic is currently ongoing, more attention should be paid to stress and lifestyle factor management in patients with T1D.
The online version contains supplementary material available at 10.1007/s13340-021-00507-4.
研究冠状病毒病（COVID-19）对1型糖尿病（T1D）患者生活方式和代谢参数的急性影响。
这项回顾性队列研究纳入了2020年4月16日至5月1日期间入住我院的34例患者。通过问卷调查获取压力水平、睡眠时间、运动、总体饮食、零食和预制食品摄入量的数据。评估从问卷调查前3个月到研究问卷调查时（大流行年份）以及从问卷调查前15个月到12个月（大流行前年份）血红蛋白A1c（HbA1c）值和体重的变化。
在COVID-19大流行期间，分别约60%和50%的参与者出现压力水平升高和运动量减少。睡眠时间减少与大流行年份3个月内的体重变化相关（r = -0.40，P = 0.043）。此外，与大流行前年份3个月内HbA1c的变化相比，大流行年份HbA1c的变化更差（大流行年份为0.12% [0.33] %，大流行前年份为-0.09 [0.39] %，P = 0.027）。
由于COVID-19大流行，许多患者经历了压力且运动减少。T1D患者的血糖控制比上一年更差。由于大流行目前仍在持续，应更加关注T1D患者的压力和生活方式因素管理。
在线版本包含可在10.1007/s13340-021-00507-4获取的补充材料。
