Lindland Are, Edward Michelet John-Thomas, Slagsvold Jon Erik
Department of Ophthalmology, Sorlandet Hospital, Norway.
Am J Ophthalmol Case Rep. 2021 Mar 31;22:101080. doi: 10.1016/j.ajoc.2021.101080. eCollection 2021 Jun.
To report on the implantation of a XEN 45 gel implant in a patient with glaucoma associated with congenital aniridia.
A 60-year old man with familial congenital aniridia and glaucoma presented with intraocular pressure of 30 mmHg in his right eye despite maximal topical treatment with four medications. Implantation of a XEN gel stent was performed without complications after subconjunctival injection of mitomycin-C (0.1 mL of 0.02%). At the two-year follow-up, the patient's intraocular pressure was 12 mmHg with one topical medication. No needling of the filtering bleb was required. No excessive fibrosis of the conjunctiva or worsening of the existing keratopathy was noted.
The XEN 45 implant could be an option in the treatment of aniridia-associated glaucoma.
报告在一名患有先天性无虹膜相关性青光眼的患者中植入XEN 45凝胶植入物的情况。
一名患有家族性先天性无虹膜和青光眼的60岁男性，尽管使用了四种药物进行最大剂量的局部治疗，但右眼眼压仍为30 mmHg。在结膜下注射丝裂霉素-C（0.02%的0.1 mL）后，植入了XEN凝胶支架，未出现并发症。在两年的随访中，患者使用一种局部药物时眼压为12 mmHg。无需对滤过泡进行针刺。未发现结膜过度纤维化或现有角膜病变恶化。
XEN 45植入物可能是治疗无虹膜相关性青光眼的一种选择。
