Rawlyk Brooklyn, Thatcher Mitchell D, Rubab Shehla, Campos-Baniak Maria Gabriela
College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Department of Ophthalmology, University of Saskatchewan, Saskatoon, SK, Canada.
Am J Ophthalmol Case Rep. 2023 Jul 7;32:101888. doi: 10.1016/j.ajoc.2023.101888. eCollection 2023 Dec.
To report a case of XEN45 gel stent implantation in a pediatric patient with WAGR syndrome as a successful surgical intervention in the management of multifactorial secondary open-angle glaucoma.
A 6-year-old female with a history of WAGR syndrome, bilateral congenital aniridia, pseudophakia OD and glaucoma OD, was referred for a XEN45 gel stent OD. IOP was persistently elevated at 24 mm Hg despite two glaucoma medications. Implantation of the XEN45 gel stent was performed using a transconjunctival ab externo approach. There were no significant intra-or-postoperative adverse events associated with the stent. The patient achieved good IOP-lowering control without glaucoma medications across the 18-month follow-up period.
A XEN45 stent through a transconjunctival ab externo approach may be an effective surgical intervention in pediatric patients with secondary open-angle glaucoma associated with aniridia and aphakia.
报告1例将XEN45凝胶支架植入患有WAGR综合征的儿科患者的病例，作为多因素继发性开角型青光眼治疗中的一种成功手术干预措施。
一名6岁女性，有WAGR综合征、双侧先天性无虹膜、右眼人工晶状体植入和右眼青光眼病史，因右眼植入XEN45凝胶支架前来就诊。尽管使用了两种青光眼药物，眼压仍持续升高至24 mmHg。采用经结膜外路植入XEN45凝胶支架。未发生与支架相关的显著术中或术后不良事件。在18个月的随访期内，患者在未使用青光眼药物的情况下眼压得到了良好控制。
经结膜外路植入XEN45支架可能是治疗与无虹膜和无晶状体相关的继发性开角型青光眼儿科患者的有效手术干预措施。
