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[纳入经颅磁刺激治疗的综合温泉疗法对慢性失眠患者睡眠质量的影响]

[The dynamics of sleep quality in patients with chronic insomnia during the complex spa treatment with the inclusion of transcranial magnetic therapy].

作者信息

Goryaev A G, Kulishova T V

机构信息

Sanatorium «Siberia», Belokurikha, Russia.

Altai State Medical University, Barnaul, Russia.

出版信息

Vopr Kurortol Fizioter Lech Fiz Kult. 2021;98(2):10-16. doi: 10.17116/kurort20219802110.

Abstract

UNLABELLED

Dissatisfaction with night sleep occurs in 45% of the population. Chronic insomnia is one of the most common sleep disorders. The incidence of insomnia is estimated at 9-15%. The clinical importance of insomnia is determined by the negative impact it has on social aspects, economic performance and human health. Taking into account the prevalence of insomnia in the population and its social importance the correct diagnosis and effective treatment of insomnia is clear.

OBJECTIVE

To assess the sleep quality dynamics in patients with chronic insomnia getting the complex spa treatment with the inclusion of transcranial magnetic therapy (TCMT).

MATERIAL AND METHODS

It was examined 122 patients (mean age 54.0±0.92 years) with a verified diagnosis of chronic insomnia; 68.9% were women and 31.1% were men. The patients were randomized into 2 groups: the main group included 62 patients who received a spa complex and TCMT; the comparison group included 60 patients who received an identical treatment complex without TCMT. All patients were evaluated by polysomnography (PSG) data, insomnia severity index (ISI) and subjective symptoms of daytime functioning.

RESULTS

As a result of treatment program implementation the patients of both groups showed a decrease in ISI and a subjective improvement in daytime well-being. In the main group the treatment led to an increase in the number of patients with mild disorders by 51.7%, a decrease in patients with moderate disorders by 16.2%, severe disorders by 45.2%, and the formation of a group of 6 people (9.7%) without sleep disorders. In the comparison group after treatment the proportion of patients with mild disorders increased by 33.3%, with moderate disorders by 3.3%, the number of patients with severe disorders decreased by 41.6%, and 3 (5%) patients had no symptoms. The mean value of ISI in the main group decreased by 35.9% (<0.001), in the comparison group - by 23.1% (<0.001), the difference was 12.8% (<0.001). From clinical perspective, patients noted an improvement in the process of falling asleep, a decrease in the number of nighttime awakenings, an increase in the duration of sleep, and an improvement in functioning while awake. After the use of therapeutic complexes in patients of both groups there was a favorable reliable dynamics in the change in PSG indicators that was more pronounced in the main group. The difference between the groups in terms of PSG was: for the wakefulness time during sleep 16.3% (<0.005), for the number of awakenings during sleep 12.8% (<0.001), for the latency of falling asleep 13.9% (<0.05), for micro-activation index 14.6% (<0.05), for sleep efficiency 4.9% (<0.05).

CONCLUSION

The inclusion of TCMT in complex spa treatment can significantly reduce ISI, the symptoms' severity of impaired daytime functioning and improve sleep quality indicators according to PSG data in patients with chronic insomnia.

摘要

未标注

45%的人群对夜间睡眠不满意。慢性失眠是最常见的睡眠障碍之一。失眠的发病率估计为9% - 15%。失眠的临床重要性取决于它对社会层面、经济表现和人类健康的负面影响。考虑到失眠在人群中的患病率及其社会重要性,对失眠进行正确诊断和有效治疗很有必要。

目的

评估接受包含经颅磁疗法(TCMT)的综合温泉治疗的慢性失眠患者的睡眠质量动态变化。

材料与方法

对122例确诊为慢性失眠的患者(平均年龄54.0±0.92岁)进行检查;其中68.9%为女性,31.1%为男性。患者被随机分为2组:主要组包括62例接受温泉综合治疗和TCMT的患者;对照组包括60例接受相同治疗但不包括TCMT的患者。所有患者均通过多导睡眠图(PSG)数据、失眠严重程度指数(ISI)和白天功能主观症状进行评估。

结果

由于治疗方案的实施,两组患者的ISI均下降,白天幸福感主观改善。主要组治疗后,轻度障碍患者数量增加51.7%,中度障碍患者减少16.2%,重度障碍患者减少45.2%,并形成了一组6人(9.7%)无睡眠障碍的患者。对照组治疗后,轻度障碍患者比例增加33.3%,中度障碍患者增加3.3%,重度障碍患者数量减少41.6%,3例(5%)患者无症状。主要组ISI的平均值下降了35.9%(<0.001),对照组下降了23.1%(<0.001),差异为12.8%(<0.001)。从临床角度看,患者注意到入睡过程有所改善,夜间觉醒次数减少,睡眠时间延长,清醒时功能改善。两组患者使用治疗组合后,PSG指标变化呈现出良好的可靠动态,主要组更为明显。两组在PSG方面的差异为:睡眠期间清醒时间16.3%(<0.005),睡眠期间觉醒次数12.8%(<0.001),入睡潜伏期13.9%(<0.05),微激活指数14.6%(<0.05),睡眠效率4.9%(<0.05)。

结论

在综合温泉治疗中加入TCMT可显著降低慢性失眠患者的ISI、白天功能受损症状的严重程度,并根据PSG数据改善睡眠质量指标。

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