编码泛素激活酶的基因可能位于X染色体上。
The gene coding a ubiquitin-activating enzyme may locate on X chromosome.
作者信息
Ohtsubo M, Nishimoto T
机构信息
Department of Moleculer Biology, Graduate School of Medical Science Kyushu University, Fukuoka, Japan.
出版信息
Biochem Biophys Res Commun. 1988 Jun 30;153(3):1173-8. doi: 10.1016/s0006-291x(88)81351-2.
PMID:3390177
Abstract
tsBN75 cells which have a ts defect in the S phase have a mutation linked to the gene of hypoxanthine phosphoribosyl transferase and cannot complement ts85 cells which have a ts defect in the ubiquitin-activating enzyme. The ubiquitin-activating enzyme may be required for completion of the S phase.
摘要
在S期存在温度敏感（ts）缺陷的tsBN75细胞有一个与次黄嘌呤磷酸核糖基转移酶基因相关的突变，并且不能对在泛素激活酶方面存在ts缺陷的ts85细胞进行互补。S期的完成可能需要泛素激活酶。
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