出院四个月后，重症新冠患者中一氧化碳弥散能力受损的情况很常见。
Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge.
作者信息
E Ekbom, R Frithiof, Öi Emilsson, Im Larson, M Lipcsey, S Rubertsson, E Wallin, C Janson, M Hultström, A Malinovschi
机构信息
Department of Medical Sciences, Respiratory-, Allergy- and Sleep Research, Uppsala University, Uppsala, Sweden.
Department of Surgical Sciences, Anaesthesiology and Intensive Care Medicine, Uppsala University, Uppsala, Sweden.
出版信息
Respir Med. 2021 Jun;182:106394. doi: 10.1016/j.rmed.2021.106394. Epub 2021 Apr 15.
Abstract
There is limited knowledge about the long-term effects on pulmonary function of COVID-19 in patients that required intensive care treatment. Spirometry and diffusing capacity for carbon monoxide (DLCO) were measured in 60 subjects at 3-6 months post discharge. Impaired lung function was found in 52% of the subjects, with reduced DLCO as the main finding. The risk increased with age above 60 years, need for mechanical ventilation and longer ICU stay as well as lower levels of C-reactive protein at admission. This suggests the need of follow-up with pulmonary function testing in intensive-care treated patients.
摘要
对于需要重症监护治疗的新冠病毒病（COVID-19）患者，其肺功能的长期影响方面的知识有限。在60名患者出院后3至6个月时进行了肺活量测定和一氧化碳弥散量（DLCO）测量。52%的患者存在肺功能受损，主要表现为DLCO降低。60岁以上、需要机械通气、在重症监护病房（ICU）停留时间更长以及入院时C反应蛋白水平较低的患者风险增加。这表明需要对接受重症监护治疗的患者进行肺功能测试随访。
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