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一项由护士主导的基于网络的过渡性护理项目对2型糖尿病患者出院后血糖控制及生活质量的影响:一项随机对照试验。

Effects of a nurse led web-based transitional care program on the glycemic control and quality of life post hospital discharge in patients with type 2 diabetes: A randomized controlled trial.

作者信息

Lyu Qi-Yuan, Huang Jie-Wei, Li Yao-Xia, Chen Qing-Ling, Yu Xiao-Xue, Wang Jia-le, Yang Qiao-Hong

机构信息

School of Nursing, Jinan University, Guangzhou, China.

Endocrinology Department, The First Affiliated Hospital of Jinan University, Guangzhou, China.

出版信息

Int J Nurs Stud. 2021 Jul;119:103929. doi: 10.1016/j.ijnurstu.2021.103929. Epub 2021 Mar 26.

Abstract

BACKGROUND

Individuals with type 2 diabetes have a heightened risk of developing serious complications post hospital discharge. Web-based transitional care is a promising intervention to improve the glycemic control and quality of life of this patient group; however, whether web-based transitional care can improve the glycemic control and quality of life of this group remains unknown. Further, the mechanisms underlying the relationships between the intervention and both glycemic control and quality of life have not been fully explored.

OBJECTIVES

The aims of this study were to develop a web-based transitional care program and evaluate its effects on the glycemic control and quality of life of Chinese patients with type 2 diabetes and to explore the mediating roles of self-efficacy and treatment adherence.

DESIGN

Randomized controlled trial.

SETTINGS AND PARTICIPANTS

This study was conducted in a large regional hospital in Guangzhou City, China. Patients diagnosed with type 2 diabetes were included.

METHODS

A total of 116 eligible participants were randomly assigned to receive either the 3-month web-based transitional care program or usual care. Assessments of hemoglobin A1c (HbA1c), self-efficacy, treatment adherence, and quality of life were conducted at baseline and at 3 months. Analysis followed the intention-to-treat principle. A generalized estimating equation was used to determine intervention effects on HbA1c and quality of life. Path analysis was used to assess the mediation of these effects by changes in self-efficacy and treatment adherence during the intervention.

RESULTS

Participants in the intervention group had significantly greater improvements in HbA1c (β = 2.87; p < 0.01) and quality of life (β = 7.69; p < 0.01) compared with the control group. The relationships between the intervention and both glycemic control and quality of life were significantly mediated by improved self-efficacy (indirect effect: β = 0.18, p < 0.05) and improved treatment adherence (indirect effect: β = 0.17, p < 0.05); overall, the model explained 52.5% of the variance in HbA1c and 34.2% of the variance in quality of life.

CONCLUSIONS

Our study identified beneficial effects of a web-based transitional care program on glycemic control and quality of life post hospital discharge in people with type 2 diabetes, and the underlying mediating mechanisms. The effectiveness and feasibility of this web-based intervention program suggests that its application should be promoted in community settings to reduce poor outcomes in people with type 2 diabetes. Tweetable abstract: The web-based transitional care program can improve patients' glycemic control and quality of life. Registration number: ChiCTR2000035603.

摘要

背景

2型糖尿病患者出院后发生严重并发症的风险增加。基于网络的过渡性护理是一种有前景的干预措施,可改善该患者群体的血糖控制和生活质量;然而,基于网络的过渡性护理能否改善该群体的血糖控制和生活质量仍不清楚。此外,干预与血糖控制和生活质量之间关系的潜在机制尚未得到充分探索。

目的

本研究旨在开发一个基于网络的过渡性护理项目,并评估其对中国2型糖尿病患者血糖控制和生活质量的影响,同时探索自我效能感和治疗依从性的中介作用。

设计

随机对照试验。

设置与参与者

本研究在中国广州市一家大型区域医院进行。纳入被诊断为2型糖尿病的患者。

方法

总共116名符合条件的参与者被随机分配接受为期3个月的基于网络的过渡性护理项目或常规护理。在基线和3个月时对糖化血红蛋白(HbA1c)、自我效能感、治疗依从性和生活质量进行评估。分析遵循意向性分析原则。使用广义估计方程来确定干预对HbA1c和生活质量的影响。路径分析用于评估干预期间自我效能感和治疗依从性的变化对这些影响的中介作用。

结果

与对照组相比,干预组参与者的HbA1c(β = 2.87;p < 0.01)和生活质量(β = 7.69;p < 0.01)有显著更大的改善。干预与血糖控制和生活质量之间的关系通过自我效能感的改善(间接效应:β = 0.18,p < 0.05)和治疗依从性的改善(间接效应:β = 0.17,p < 0.05)得到显著中介;总体而言,该模型解释了HbA1c变异的52.5%和生活质量变异的34.2%。

结论

我们的研究确定了基于网络的过渡性护理项目对2型糖尿病患者出院后血糖控制和生活质量的有益影响以及潜在的中介机制。这种基于网络的干预项目的有效性和可行性表明,应在社区环境中推广其应用,以减少2型糖尿病患者的不良结局。可发推文摘要:基于网络的过渡性护理项目可改善患者的血糖控制和生活质量。注册号:ChiCTR2000035603。

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