Helbig Stefanie, Eule J Corinna
Klinik für kleine Haustiere der Freien Universität Berlin.
Tierarztl Prax Ausg K Kleintiere Heimtiere. 2021 Apr;49(2):86-92. doi: 10.1055/a-1197-4709. Epub 2021 Apr 26.
Using tonometers, intraocular pressure (IOP) is merely measured indirectly leading to measurement inaccuracies. All available technical devices are designed for humans, hence a calibration via comparison to manometric measurements is necessary for their use in veterinary medicine. In this study, the applanation tonometer Tono-Pen Avia Vet™ (TPA) was to be calibrated for use in dogs and cats resulting in the calculation of a correction factor. Additional objectives were the determination of reference values for TPA-derived IOP and the evaluation of possible influence of patient characteristics on measurements results.
For the manometric study, 10 enucleated eyes from cats and dogs were subject to IOP measurement with a manometer and the TPA covering the range of 5-60 mmHg. The mean percentage of difference between manometer and TPA was used to calculate correction factors. Subsequently, the TPA was employed to measure the IOP in healthy animals without signs of ocular disease for the determination of reference values. The effect of the patient characteristics age, body weight, and gender on the IOP measurement results was examined using statistical mixed models.
With rising intraocular pressure, the TPA underestimated IOP to an increasing degree. Multiplication of the TPA-derived IOP with the factor of 1.5 for dogs and cats resulted in values well in accordance with the manometrically-derived, actual IOP. In the second part of the study, a total of 94 dogs (188 eyes) and 64 cats (128 eyes) were examined. Reference values for the IOP measured with the TPA are 9-18 mmHg for dogs and 9-20 mmHg for cats. For both species, age exhibited a significant influence (dog, p = 0.001 and cat, p = 0.008) on the IOP measurement results in that the IOP-values displayed a decrease with increasing age.
The TPA underestimated the actual IOP with increasing intraocular pressure. The calculated correction factor of 1.5 is suitable for the conversion of tonometric IOP results into actual pressure values.
The TPA is suitable for the measurement of the IOP in dogs and cats.
使用眼压计测量眼内压（IOP）只是一种间接测量方式，会导致测量不准确。所有现有的技术设备都是为人类设计的，因此在兽医学中使用这些设备时，需要通过与压力测量结果进行比较来进行校准。在本研究中，对用于犬猫的压平眼压计Tono-Pen Avia Vet™（TPA）进行校准，以计算校正因子。其他目标是确定TPA测量的IOP的参考值，并评估患者特征对测量结果的可能影响。
在压力测量研究中，用压力计和TPA对10只来自猫和狗的摘除眼球进行眼压测量，眼压范围为5-60 mmHg。用压力计和TPA之间的平均差异百分比来计算校正因子。随后，使用TPA测量无眼部疾病迹象的健康动物的眼压，以确定参考值。使用统计混合模型检查患者特征年龄、体重和性别对眼压测量结果的影响。
随着眼压升高，TPA低估眼压的程度越来越大。将犬猫TPA测量的眼压乘以1.5的因子，得到的值与压力测量得出的实际眼压非常一致。在研究的第二部分，共检查了94只狗（188只眼）和64只猫（128只眼）。用TPA测量的眼压参考值，狗为9-18 mmHg，猫为9-20 mmHg。对于这两个物种，年龄对眼压测量结果均有显著影响（狗，p = 0.001；猫，p = 0.008），即眼压值随年龄增长而降低。
随着眼压升高，TPA低估了实际眼压。计算得出的1.5的校正因子适用于将眼压计测量的眼压结果转换为实际压力值。
TPA适用于测量犬猫的眼压。
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