Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Department of Biostatistics and Medical Informatics, Institute for Clinical and Translational Research (ICTR, University of Wisconsin-Madison, Madison, WI, USA.
Vet Ophthalmol. 2021 Mar;24 Suppl 1(Suppl 1):194-198. doi: 10.1111/vop.12877. Epub 2021 Feb 27.
To evaluate the effect of latex tip cover manufacturer on accuracy and repeatability of Tono-Pen Vet™ in canine eyes.
Twelve enucleated globes from six dogs.
The anterior chamber was cannulated and connected to a calibrated manometer. Intraocular pressure (IOP) measurements were obtained using the Tono-Pen Vet and TONOVET Plus at manometric IOP ranging from 5 to 80 mmHg. At each IOP, the Tono-Pen Vet was used with a new Ocu-Film™ latex tip cover (the only manufacturer-approved brand of cover) followed by a new Softips™ latex tip cover. For comparison, the TONOVET Plus was also used at each IOP with a new disposable rebound probe. Measured IOP values were analyzed by linear regression and intraclass correlation coefficient (ICC).
Tono-Pen Vet accuracy was unaffected by tip cover manufacturer or by frequent change in cover. Using ICC analysis, repeatability of measurements using either tonometer was good to excellent at physiologic IOP levels but variably decreased with both devices at supraphysiologic IOP.
Neither tip cover manufacturer nor frequent changes in tip cover adversely affect Tono-Pen Vet accuracy. Measurement repeatability with Tono-Pen Vet and TONOVET Plus is widely variable at supraphysiologic IOP. Therefore, minor changes in IOP >25 mmHg should not be used to make clinical decisions without considering this variability.
评估乳胶探头盖制造商对犬眼 Tono-Pen Vet™准确性和可重复性的影响。
来自 6 只狗的 12 个眼球。
前房被穿刺并连接到校准的压力计。使用 Tono-Pen Vet 和 TONOVET Plus 在眼压(IOP)范围为 5 至 80mmHg 的情况下进行眼压测量。在每个 IOP 下,使用新的 Ocu-Film™乳胶探头盖(唯一经制造商批准的探头盖品牌)和新的 Softips™乳胶探头盖后,使用 Tono-Pen Vet 进行测量。为了比较,在每个 IOP 下,还使用新的一次性回弹探头对 TONOVET Plus 进行测量。分析测量的眼压值采用线性回归和组内相关系数(ICC)。
探头盖制造商或探头盖的频繁更换均不影响 Tono-Pen Vet 的准确性。使用 ICC 分析,两种眼压计在生理 IOP 水平下的测量重复性均为良好至优秀,但在两种设备的高眼压下,重复性均有所下降。
探头盖制造商或探头盖的频繁更换均不会对 Tono-Pen Vet 的准确性产生不利影响。Tono-Pen Vet 和 TONOVET Plus 的测量重复性在高眼压时差异较大。因此,在不考虑这种变异性的情况下,不应仅根据 IOP 变化>25mmHg 来做出临床决策。