Antti-Poika I, Karaharju E, Roine R, Salaspuro M
Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Finland.
Alcohol Alcohol. 1988;23(2):115-21.
We studied 120 injured male patients of working age who were heavy drinkers or alcoholics, obtaining seven points or more in the Michigan Alcoholism Screening Test (MAST). They were randomly allocated either to an intervention group (IG) or to a control group (CG). In addition to the MAST interview, the consumption of alcohol during the previous week prior to hospital admission was calculated and laboratory measures (serum GGT, ASAT and ALAT) were obtained. Counselling of the patients in the IG was carried out by a trained assistant nurse and a physician. Forty-nine patients in IG and 40 patients in CG were re-examined after 6 months. In the IG 45% and in the CG 20% of the patients were improved (Chi square test, P less than 0.05). Improvement criteria were a decrease in alcohol consumption by at least one-third and decrease of S-GGT by at least 20% during the follow-up period. In respect to the laboratory measures the groups were identical at the beginning of the study and after 6 months' follow-up. Our results are encouraging and suggest that the assessment of heavy drinking should be a routine in the treatment of alcohol-related injuries and that education and counselling must be intensive to be effective.
我们研究了120名工作年龄的男性受伤患者,他们均为重度饮酒者或酗酒者,在密歇根酒精ism筛查测试(MAST)中得分7分或更高。他们被随机分配到干预组(IG)或对照组(CG)。除了进行MAST访谈外,还计算了入院前一周的酒精消费量,并获取了实验室测量值(血清γ-谷氨酰转移酶、天冬氨酸转氨酶和丙氨酸转氨酶)。IG组的患者由一名经过培训的助理护士和一名医生进行咨询。6个月后对IG组的49名患者和CG组的40名患者进行了复查。IG组45%的患者和CG组20%的患者病情有所改善(卡方检验,P小于0.05)。改善标准为随访期间酒精消费量减少至少三分之一,血清γ-谷氨酰转移酶降低至少20%。在实验室测量方面,两组在研究开始时和随访6个月后情况相同。我们的结果令人鼓舞,表明对重度饮酒的评估应成为酒精相关损伤治疗中的常规操作,并且教育和咨询必须强化才能有效。