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对男同性恋艾滋病毒阳性和阴性人群咽部沙眼衣原体的初步研究。

Pilot study of pharyngeal Chlamydia trachomatis in HIV-positive and HIV-negative men who have sex with men.

作者信息

Samarasekara Keshinie, Fitzpatrick Colin, Finnerty Fionnuala, Richardson Daniel

机构信息

Sexual Health and HIV Medicine, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.

Sexual Health and HIV Medicine, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK; and Sexual Health and HIV Medicine, Brighton and Sussex Medical School, Brighton, UK; and Corresponding author. Email:

出版信息

Sex Health. 2021 May;18(2):200-201. doi: 10.1071/SH20218.

DOI:10.1071/SH20218
PMID:33902811
Abstract

Unlike pharyngeal Neisseria gonorrhoeae, less is known about pharyngeal Chlamydia trachomatis in men who have sex with men (MSM). We reviewed cases of pharyngeal chlamydia in MSM from January to December 2019. The overall prevalence of pharyngeal chlamydia was 75/6613 (1.13%; 95% confidence interval (CI) = 0.9-1.14). The median number of sexual partners was three, four (5%) reported throat symptoms and 20 (26%) were HIV positive. Multi-site and concomitant infection was common: rectal chlamydia [39 (52%)], urethral chlamydia [12 (16%)], early syphilis [2 (3%)] and gonorrhoea [14 (19%)]. HIV-positive MSM with pharyngeal chlamydia were older (P = 0.02) and more likely to have had previous syphilis (odds ratio = 4.9; 95% CI = 1.6-14.7; P = 0.005). Further research is needed to explore the characteristics of pharyngeal chlamydia and benefits of increased screening for asymptomatic pharyngeal chlamydia in MSM.

摘要

与咽部淋病奈瑟菌不同,对于男男性行为者(MSM)咽部沙眼衣原体的了解较少。我们回顾了2019年1月至12月MSM中咽部衣原体感染的病例。咽部衣原体的总体患病率为75/6613(1.13%;95%置信区间(CI)=0.9-1.14)。性伴侣的中位数为3个,4人(5%)报告有咽喉症状,20人(26%)为HIV阳性。多部位和合并感染很常见:直肠衣原体感染[39例(52%)]、尿道衣原体感染[12例(16%)]、早期梅毒[2例(3%)]和淋病[14例(19%)]。感染咽部衣原体的HIV阳性MSM年龄较大(P=0.02),且更有可能曾患梅毒(比值比=4.9;95%CI=1.6-14.7;P=0.005)。需要进一步研究以探索咽部衣原体的特征以及增加对MSM无症状咽部衣原体筛查的益处。

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