全有机三重动态组合库的同步形成
Simultaneous Formation of a Fully Organic Triply Dynamic Combinatorial Library.
作者信息
Drożdż Wojciech, Walczak Anna, Stefankiewicz Artur R
机构信息
Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland.
Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61-614 Poznań, Poland.
出版信息
Org Lett. 2021 May 7;23(9):3641-3645. doi: 10.1021/acs.orglett.1c01042. Epub 2021 Apr 27.
Here we report the simultaneous formation of doubly and triply dynamic libraries as a result of exchange reactions between functionalized organic building blocks. A combination of three different reversible covalent linkages involving a boronate ester transesterification along with an imine and disulfide exchange was employed to generate a new type of fully organic triply dynamic molecular assembly.
在此，我们报告了由于功能化有机结构单元之间的交换反应而同时形成双动态和三动态库的情况。我们采用了三种不同的可逆共价键组合，包括硼酸酯酯交换反应以及亚胺和二硫键交换反应，以生成一种新型的全有机三动态分子组装体。
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