Chief of Surgery Service16573, Hospital de Antequera, 16752University of Malaga, Málaga, Spain.
Digestive Surgeon, Service of Surgery,16573Hospital de Antequera, 16752University of Malaga, Málaga, Spain.
Surg Innov. 2022 Feb;29(1):50-55. doi: 10.1177/15533506211015196. Epub 2021 Apr 27.
In the last two decades, many sphincter preservation techniques have been proposed for the treatment of anal fistula. Since 2011, our surgical team has treated fistulas by sealing them with platelet-rich fibrin (PRF). This is performed actually as an outpatient process, without anaesthesia.
Patients were treated with PRF sealant, during the period June 2012-March 2017. The fibrin preparation is applied in the fistulous tract, with no need for any type of anaesthesia, and so the patient can go home immediately afterwards, without further observation.
After an average follow-up of 26.49 months, the perianal fistula had healed completely in 52.86% of the patients (n = 37), who each received an average of 1.92 sealant operations. In another 10 cases, the sealing was initially successful, but a relapse occurred during the follow-up period.
The outpatient treatment of perianal fistula with PRF is totally harmless, is very low cost and achieves very acceptable results. In our opinion, therefore, this could be considered an appropriate initial treatment for perianal fistula, with surgical treatment being reserved if this approach is unsuccessful, thereby avoiding many complications and producing significant economic savings for the health system.
在过去的二十年中,已经提出了许多括约肌保留技术来治疗肛瘘。自 2011 年以来,我们的外科团队一直通过用富含血小板的纤维蛋白(PRF)密封来治疗瘘管。实际上,这是一种门诊手术,无需麻醉。
在 2012 年 6 月至 2017 年 3 月期间,患者接受了 PRF 密封剂治疗。纤维蛋白制剂应用于瘘管中,无需任何类型的麻醉,因此患者可以立即回家,无需进一步观察。
平均随访 26.49 个月后,52.86%(n=37)的患者完全愈合,平均接受了 1.92 次密封操作。在另外 10 例中,最初的密封是成功的,但在随访期间复发。
PRF 门诊治疗肛周瘘管是完全无害的,成本非常低,效果非常理想。因此,我们认为这可以被视为肛周瘘管的一种合适的初始治疗方法,如果这种方法不成功,可以保留手术治疗,从而避免许多并发症,并为医疗系统节省大量费用。