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单性雌雄日本血吸虫在终末宿主内的生存和繁殖潜力的延长。

Extended survival and reproductive potential of single-sex male and female Schistosoma japonicum within definitive hosts.

机构信息

Department of Epidemiology and Statistics, School of Public Health, Soochow University, Suzhou, China; Key Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, China.

Department of Epidemiology and Statistics, School of Public Health, Soochow University, Suzhou, China; Key Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, China.

出版信息

Int J Parasitol. 2021 Oct;51(11):887-891. doi: 10.1016/j.ijpara.2021.03.005. Epub 2021 Apr 24.

DOI:10.1016/j.ijpara.2021.03.005
PMID:33905765
Abstract

Schistosomiasis is caused by dioecious helminths of the genus Schistosoma. Recent work indicated that unpaired female and male schistosomes can survive within their definitive host for at least 1 year, although the viability or fertility of these worms after subsequent pairing remained untested. We performed two experiments on laboratory mice, one with female Schistosoma japonicum exposure first and male schistosomes second and another vice versa. After surviving as single-sex unpaired forms for up to 1 year, 58.5% of male and 70% of female schistosomes were able to mate and produce viable eggs. This highlights an additional biological challenge in achieving elimination of schistosomiasis.

摘要

血吸虫病由雌雄同体的血吸虫属寄生虫引起。最近的研究表明,雌雄异体的血吸虫在其终宿主体内至少可以存活 1 年,尽管这些蠕虫在随后的配对后是否具有活力或生育能力仍未得到测试。我们在实验室小鼠上进行了两项实验,一项是先暴露于雌性日本血吸虫,然后暴露于雄性血吸虫,另一项则相反。在作为单性未配对形式存活长达 1 年后,58.5%的雄性和 70%的雌性血吸虫能够交配并产生有活力的卵子。这突出了实现消除血吸虫病的另一个生物学挑战。

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