Stepanov S S, Semchenko V V
Biull Eksp Biol Med. 1988 Jun;105(6):728-30.
Using PTA technique, the organization of subsynaptic units (paramembrane specialized formations of the cytoskeleton) was revealed in the molecular layer of the rat neocortex during post-asphyxia period. The density and summarized length of the active contact zone (ACZ) with different degree of maturity of subsynaptic units were calculated and the information was evaluated. It was revealed that the total length of ACZ synapses was restored to the control level on the 7th day after asphyxia and the information of the synaptic pool was 30.1% on the 14th day, in spite of a significant deficiency in the synapse density. The information of the synaptic pool was restored mainly due to hypertrophy of interneuronal contacts with well developed presynaptic grating.
采用磷钨酸(PTA)技术,在窒息后大鼠新皮质分子层中揭示了突触下单位(细胞骨架的膜旁特化结构)的组织情况。计算了具有不同成熟度突触下单位的活性接触区(ACZ)的密度和总长度,并对相关信息进行了评估。结果显示,窒息后第7天ACZ突触的总长度恢复到对照水平,尽管突触密度显著不足,但在第14天突触池信息为30.1%。突触池信息的恢复主要归因于具有发育良好突触前栅的中间神经元接触的肥大。