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[复苏后期新皮质突触构筑的重组模式]

[Reorganization patterns in the synaptic architectonics of the neocortex in the postresuscitation period].

作者信息

Semchenko V V, Stepanov S S, Chesnokov Iu V

出版信息

Biull Eksp Biol Med. 1982 Dec;94(12):95-6.

PMID:7150776
Abstract

Staining of brain tissue with phosphotungstic acid was used to assay interneuronal contacts in the molecular layer of the cerebral cortex of rats with a history of clinical death because of hemorrhage and asphyxia. Common regularities of reconstruction of neocortical architectonics during the resuscitation period were defined. Marked reduction in the number of synapses was discovered in the neocortex. The main form of destruction of the contacts was the light type of destruction. Hypertrophy of the remaining synapses occurs in the early periods. The processes of neosynaptogenesis get activated on day 7. Both the types of structural recovery of the synaptic pool (hypertrophy and neoformation of the contacts) were fairly marked in the long-term period.

摘要

用磷钨酸对脑组织进行染色,以检测有因出血和窒息导致临床死亡病史的大鼠大脑皮质分子层中的神经元间接触。确定了复苏期新皮质结构重建的常见规律。发现新皮质中突触数量明显减少。接触破坏的主要形式是轻度破坏类型。在早期,剩余突触会发生肥大。在第7天,新突触形成过程被激活。在长期观察中,突触池结构恢复的两种类型(接触的肥大和新形成)都相当明显。

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