Fan S T, Choi T K, Lai C S, Wong J
Department of Surgery, University of Hong Kong, Queen Mary Hospital.
Br J Surg. 1988 May;75(5):463-6. doi: 10.1002/bjs.1800750520.
The influence of age on the mortality rate of 268 patients with acute pancreatitis was studied. The hospital mortality rate for patients aged below 50 years was 5.9 per cent. The figure increased to 21.3 per cent in patients aged over 75; the high mortality was accounted for by a higher incidence of deaths related to concomitant medical or surgical diseases in the same hospital admission rather than to complications resulting directly from the pathological process of acute pancreatitis. When only deaths due to complications of acute pancreatitis were analysed, the mortality rate was not significantly different between the young and elderly groups. Moreover, the complication rate and the proportion of patients having severe disease (judged by the number of prognostic signs) were not higher in the elderly. Thus acute pancreatitis was intrinsically not more serious were it not for the presence of concomitant diseases with advanced age.
研究了年龄对268例急性胰腺炎患者死亡率的影响。50岁以下患者的医院死亡率为5.9%。75岁以上患者的这一数字升至21.3%;高死亡率是由于在同一次住院期间与伴随的内科或外科疾病相关的死亡发生率较高,而非急性胰腺炎病理过程直接导致的并发症。当仅分析急性胰腺炎并发症导致的死亡时,青年组和老年组的死亡率无显著差异。此外,老年组的并发症发生率和重症患者比例(根据预后体征数量判断)并不更高。因此,若不存在老年患者伴随的疾病,急性胰腺炎本质上并不更严重。