Varshney Bharti, Choudhary Gautam Ram, Yadav Taruna, Nalwa Aasma
Pathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Urology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
BMJ Case Rep. 2021 Apr 27;14(4):e240768. doi: 10.1136/bcr-2020-240768.
Sarcomatoid urothelial carcinoma is a rare aggressive malignant neoplasm of the urinary bladder. It usually presents at an advanced stage and thus carries a poor prognosis. These tumours are usually managed with multimodal therapies such as cystectomy and chemotherapy. In the present case, a 72-year-old man presented with gross haematuria and was diagnosed as sarcomatoid urothelial carcinoma with chondrosarcomatous differentiation and extensive stromal osseous metaplasia. The patient was managed with transurethral resection of bladder tumour (TURBT), followed by intravesical chemotherapy. The patient is doing well post 14 months follow-up. Hence, complete TURBT with chemotherapy is also a viable option for patients who prefer to preserve bladder.
肉瘤样尿路上皮癌是一种罕见的侵袭性膀胱恶性肿瘤。它通常在晚期出现，因此预后较差。这些肿瘤通常采用多模式治疗，如膀胱切除术和化疗。在本病例中，一名72岁男性因肉眼血尿就诊，被诊断为具有软骨肉瘤分化和广泛间质骨化生的肉瘤样尿路上皮癌。该患者接受了经尿道膀胱肿瘤切除术（TURBT），随后进行膀胱内化疗。经过14个月的随访，患者情况良好。因此，对于希望保留膀胱的患者，完整的TURBT联合化疗也是一种可行的选择。
