Dallel R, Raboisson P, Auroy P, Woda A
Laboratoire de Physiologie Orofaciale, Faculté de Chirurgie Dentaire, Clermont Ferrand, France.
Brain Res. 1988 May 10;448(1):7-19. doi: 10.1016/0006-8993(88)91096-7.
Single units responsive to noxious mechanical stimulation of orofacial receptive fields were recorded within the ventrobasal complex of the rat thalamus. The induced activities were compared before and after deafferentation of the subnucleus caudalis by a trigeminal tractotomy performed at the obex level. The receptive fields activated by noxious stimulation were classified as 'oral' when included in the oral, perioral or paranasal areas, and as 'facial' when included in facial regions distant from the oral cavity. After tractotomy, the unit responses to noxious stimulation of an oral field remained unchanged in 8 cases, decreased in 3 cases, and were suppressed in 4 cases. For units responding to noxious stimulation of a facial field, the responses were suppressed in 8 cases, decreased in two cases and remained unchanged in two other cases. So it appears that the rostral part of the trigeminal sensory complex (1) receives nociceptive afferents mainly from the oral and perioral areas and (2) is a relay in ascending pathways which convey painful sensations.
在大鼠丘脑腹侧基底复合体中记录到对口腔面部感受野有害机械刺激有反应的单个神经元。通过在闩平面进行三叉神经束切断术，使尾侧亚核传入神经切断前后，比较诱发的活动。当有害刺激激活的感受野包括口腔、口周或鼻旁区域时，被分类为“口腔”感受野；当包括远离口腔的面部区域时，则被分类为“面部”感受野。束切断术后，8例对口腔感受野有害刺激的单位反应保持不变，3例降低，4例受到抑制。对于对面部感受野有害刺激有反应的单位，8例反应受到抑制，2例降低，另外2例保持不变。因此，三叉神经感觉复合体的头端部分似乎（1）主要接收来自口腔和口周区域的伤害性传入神经，并且（2）是传递疼痛感觉的上行通路中的一个中继站。
