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[已撤回] 茵芋碱对U937人白血病细胞的抗癌作用是通过线粒体介导的凋亡、细胞周期阻滞和对癌细胞迁移的抑制来实现的。

[Retracted] and anticancer effects of marmesin in U937 human leukemia cells are mediated via mitochondrial‑mediated apoptosis, cell cycle arrest, and inhibition of cancer cell migration.

作者信息

Dong Lin, Xu Wen-Wei, Li Hong, Bi Ke-Hong

机构信息

Department of Hematology, Qianfoshan Hospital Affiliated to Shandong University, Jinan, Shandong 250014, P.R. China.

出版信息

Oncol Rep. 2021 Jun;45(6). doi: 10.3892/or.2021.8065. Epub 2021 Apr 28.

Abstract

Following the publication of the above paper, a concerned reader drew to the Editor's attention that a pair of tumors in Fig. 10 appeared to have been duplicated, although one of the tumors appeared at a larger size in the figure relative to the first one. Furthermore, the flow cytometric plots shown in Fig. 2B in the above paper appeared to be remarkably similar to data presented in a paper published in Phytomedicine [Sui C‑G, Meng F‑D and Jiang Y‑H: Antiproliferative activity of rosamultic acid is associated with induction of apoptosis, cell cycle arrest, inhibition of cell migration and caspase activation in human gastric cancer (SGC‑7901) cells.  22: 796‑806, 2015]. After having conducted an independent investigation in the Editorial Office, the Editor of has determined that the above paper should be retracted from the Journal on account of a lack of confidence concerning the originality and the authenticity of the data. The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal. [the original article was published in 39: 597‑602, 2018; DOI: 10.3892/or.2017.6147].

摘要

上述论文发表后,一位关注此事的读者提请编辑注意,图10中的一对肿瘤似乎被重复了,尽管其中一个肿瘤在图中相对于第一个肿瘤显得更大。此外,上述论文图2B中所示的流式细胞仪图似乎与发表在《植物医学》上的一篇论文[隋C-G,孟F-D和姜Y-H:迷迭香酸的抗增殖活性与人胃癌(SGC-7901)细胞凋亡诱导、细胞周期阻滞、细胞迁移抑制和半胱天冬酶激活有关。22: 796-806,2015]中呈现的数据非常相似。编辑部进行独立调查后,《》杂志的编辑决定,鉴于对数据的原创性和真实性缺乏信心,应从该期刊撤回上述论文。已要求作者对这些问题作出解释,但编辑部从未收到任何答复。编辑对给该期刊读者带来的任何不便表示歉意。[原文发表于《》39: 597-602,2018;DOI: 10.3892/or.2017.6147]

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