一种用于 MR 成像和三阴性乳腺癌治疗的多模式治疗的 PDA-DTC/Cu-MnO 纳米平台。
A PDA-DTC/Cu-MnO nanoplatform for MR imaging and multi-therapy for triple-negative breast cancer treatment.
机构信息
Breast Cancer Center, Shanghai East Hospital, School of Medicine, Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, P. R. China.
Breast Cancer Center, Shanghai East Hospital, Nanjing Medical University, Shanghai 200120, P. R. China.
出版信息
Chem Commun (Camb). 2021 Apr 27;57(34):4158-4161. doi: 10.1039/d1cc00987g.
Herein, a multi-functional nanoplatform (PDA-DTC/Cu-MnO2) was established, which has been employed for MR imaging-guided multi-therapy (CDT, PTT and chemotherapy) for cancer treatment. The in vitro and in vivo results confirmed that the biocompatible nanoplatform could significantly induce tumor cell death and inhibit tumor growth.
在此，建立了一种多功能纳米平台（PDA-DTC/Cu-MnO2），用于磁共振成像引导的多疗法（CDT、PTT 和化疗）治疗癌症。体外和体内结果证实，这种生物相容性纳米平台能够显著诱导肿瘤细胞死亡并抑制肿瘤生长。
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