Li Shengnan, Cong Yang, Fu Jun
Key Laboratory of Polymeric Composite and Functional Materials of Ministry of Education, Guangdong Functional Biomaterials Engineering Technology Research Center, Guangzhou Key Laboratory of Flexible Electronic Materials and Wearable Devices, School of Materials Science and Engineering, Sun Yat-sen University, 135 Xingang Road West, Guangzhou 510275, China.
College of Materials Science and Chemical Engineering, Ningbo University of Technology, Ningbo 315201, China.
J Mater Chem B. 2021 Jun 2;9(22):4423-4443. doi: 10.1039/d1tb00523e.
Flexible bioelectronics have promising applications in electronic skin, wearable devices, biomedical electronics, etc. Hydrogels have unique advantages for bioelectronics due to their tissue-like mechanical properties and excellent biocompatibility. Particularly, conductive and tissue adhesive hydrogels can self-adhere to bio-tissues and have great potential in implantable wearable bioelectronics. This review focuses on the recent progress in tissue adhesive hydrogel bioelectronics, including the mechanism and preparation of tissue adhesive hydrogels, the fabrication strategies of conductive hydrogels, and tissue adhesive hydrogel bioelectronics and applications. Some perspectives on tissue adhesive hydrogel bioelectronics are provided at the end of the review.
柔性生物电子学在电子皮肤、可穿戴设备、生物医学电子学等领域有着广阔的应用前景。水凝胶因其类似组织的机械性能和优异的生物相容性,在生物电子学方面具有独特优势。特别是,导电且具有组织粘附性的水凝胶能够自粘附于生物组织,在可植入可穿戴生物电子学领域具有巨大潜力。本文综述聚焦于组织粘附性水凝胶生物电子学的最新进展,包括组织粘附性水凝胶的作用机制与制备、导电水凝胶的制造策略,以及组织粘附性水凝胶生物电子学及其应用。综述结尾对组织粘附性水凝胶生物电子学给出了一些展望。