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美国国立卫生研究院和意大利中毒控制中心网络:一项针对化学品暴露监测的合作研究结果。

The National Institute of Health and the Italian Poison Centers Network: results of a collaborative study for the surveillance of exposures to chemicals.

机构信息

National Center for Chemicals, Cosmetics and Consumer Protection, Istituto Superiore di Sanità, Rome, Italy.

Poison Centre of Puglia, Policlinico Riuniti di Foggia, Italy.

出版信息

Ann Ig. 2022 Mar-Apr;34(2):137-149. doi: 10.7416/ai.2021.2454. Epub 2021 Apr 30.

DOI:10.7416/ai.2021.2454
PMID:33908599
Abstract

BACKGROUND

The Public Health Surveillance Systems are essential to improve and protect public health, as highlighted by the World Health Organization. According with this consideration, a systematic collaboration between the National Institute of Health and the Poison Centers of Northern, Central and Southern Italy was established. Its aim was to improve the national network for the surveillance of dangerous exposures to chemicals. The developed network provided harmonized data essential for evidence-based interventions and significantly ameliorated the data flow between the Poison Centers and the Central Health Institutions.

METHODS

The improvement of the system was obtained through several actions, such as the development of the "Online Surveillance Card" for the detection of sentinel events in real time and the harmonization of the data collection flow, including the product categorization according to the European Product Categorization System. Data analysis was carried out by Microsoft's IBM SPSS Statistics version 26, Access and Excel.

RESULTS

Important information was obtained, regarding also exposures to chemicals and their management in pediatric populations. The surveillance network was proved effective not only under "normal" conditions but also to promptly monitor changes during exceptional health emergencies, such as the COVID-19 pandemic. During the 2020 lockdown the surveillance system registered a significant increase in the frequency of exposures to disinfectants (p-value=0.002), an evidence that highlighted the need of tailored intervention.

CONCLUSIONS

This Italian Project model proves to be reliable and suitable to be transferred to other European countries, in order to realize an European Poison Centers' Network, able to overcome unsolved health problems and to globally improve the "evidence-based" prevention of exposures to chemicals.

摘要

背景

正如世界卫生组织所强调的那样,公共卫生监测系统对于改善和保护公共卫生至关重要。基于这一考虑,意大利北部、中部和南部的国家健康研究所与中毒中心之间建立了系统的合作关系。其目的是改善国家网络,以监测对化学品的危险暴露。开发的网络提供了基于证据的干预措施所必需的协调数据,并显著改善了中毒中心和中央卫生机构之间的数据流动。

方法

通过多项措施提高了系统的效率,例如开发“在线监测卡”,实时发现哨兵事件,以及协调数据收集流程,包括根据欧洲产品分类系统对产品进行分类。数据分析使用 Microsoft 的 IBM SPSS Statistics 版本 26、Access 和 Excel 进行。

结果

还获得了关于儿科人群中化学物质暴露及其管理的重要信息。监测网络不仅在“正常”情况下有效,而且在异常卫生紧急情况下(如 COVID-19 大流行)也能迅速监测变化。在 2020 年封锁期间,监测系统记录到消毒剂暴露的频率显著增加(p 值=0.002),这一证据表明需要采取有针对性的干预措施。

结论

意大利项目模型被证明是可靠的,适合转移到其他欧洲国家,以建立一个欧洲中毒中心网络,能够解决未解决的健康问题,并在全球范围内改善对化学物质暴露的“基于证据”预防。

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