Center for Weight, Eating, and Lifestyle Science, Drexel University, Philadelphia, Pennsylvania, USA.
Department of Psychology, Drexel University, Philadelphia, Pennsylvania, USA.
Int J Eat Disord. 2021 Jul;54(7):1316-1322. doi: 10.1002/eat.23528. Epub 2021 Apr 28.
Reduced exposure to social reward during the COVID-19 pandemic may result in both reduced reward response to day-to-day life activities and elevated reward response to substances or naturally rewarding stimuli (e.g., food). The combined hypo- and hyper-reward responses results in a reward imbalance, which has been noted as a relevant maintenance factor for eating disorders (EDs) characterized by binge eating. This registered report describes the protocol for a pilot randomized controlled trial (RCT) comparing supportive therapy to a novel treatment targeting reward imbalance (Reward Re-Training; RRT) for individuals with binge eating. Aims of the current study include to confirm feasibility and acceptability of RRT, to evaluate the ability of RRT to engage critical targets, and to provide preliminary estimates of efficacy in reducing ED symptoms at both posttreatment and 3-month follow-up. Sixty participants will be randomized to either RRT or supportive therapy. For both conditions, treatment will be delivered in 10 weekly group outpatient therapy sessions conducted remotely using videoconferencing software. Assessments will be conducted at baseline, mid-treatment, posttreatment, and 3-month follow-up to measure feasibility, acceptability, critical treatment targets (i.e., reward to day-to-day life activities, reward to palatable foods, social isolation, and loneliness), and ED symptoms.
在 COVID-19 大流行期间,社交奖励的减少可能导致日常生活活动的奖励反应减少,而对物质或自然奖励刺激(例如食物)的奖励反应升高。这种低反应和高反应的综合反应导致了奖励失衡,这被认为是暴食障碍(ED)的一个相关维持因素。本注册报告描述了一项针对暴食个体的支持性治疗与针对奖励失衡的新型治疗(奖励再训练;RRT)的随机对照试验(RCT)的方案。本研究的目的包括确认 RRT 的可行性和可接受性,评估 RRT 对关键目标的作用能力,并提供治疗后和 3 个月随访时减少 ED 症状的初步疗效估计。60 名参与者将随机分配到 RRT 或支持性治疗组。对于两种情况,治疗将通过使用视频会议软件远程进行的 10 次每周团体门诊治疗来提供。评估将在基线、治疗中期、治疗后和 3 个月随访时进行,以测量可行性、可接受性、关键治疗目标(即对日常生活活动的奖励、对美味食物的奖励、社会隔离和孤独感)和 ED 症状。