可转座遗传元件作为基因不稳定和染色体重排的因子。
Transposable genetic elements as agents of gene instability and chromosomal rearrangements.
作者信息
Nevers P, Saedler H
出版信息
Nature. 1977 Jul 14;268(5616):109-15. doi: 10.1038/268109a0.
DOI:10.1038/268109a0
PMID:339095
Abstract
Transposable genetic elements in prokaryotes and eukaryotes, when inserted at a given locus, can control expression of the locus and cause large scale rearrangements of adjacent DNA sequences. Striking similarities in genetic behaviour between the two groups of elements have led to the proposal of a molecular model of eukaryotic controlling elements, and to suggestions about the part such elements may play in evolution and differentiation.
摘要
原核生物和真核生物中的转座遗传元件，当插入到特定基因座时，可控制该基因座的表达，并导致相邻DNA序列的大规模重排。两组元件在遗传行为上的显著相似性，引发了真核生物控制元件分子模型的提出，以及关于此类元件在进化和分化中可能发挥的作用的推测。
Zotero 插件