Nakajima Medical Clinic, Kobe, Japan.
Division of Respiratory Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine, Kobe, Japan
In Vivo. 2021 May-Jun;35(3):1799-1803. doi: 10.21873/invivo.12440.
BACKGROUND/AIM: The aim of this study was to elucidate the significance of allergic rhinitis and post-nasal drip symptoms in patients with cough-variant and cough-predominant asthma.
We conducted a retrospective analysis of 91 patients who had cough-variant or cough-predominant asthma and first visited the Nakajima Medical Clinic in Japan between June 2012 and July 2015.
Post-nasal drip symptoms were reported in 58 (63.7%) patients. The patients with post-nasal drip symptoms (19.5±8.3 days) had a significantly longer time until cough disappearance than those without post-nasal drip symptoms (11.0±4.8 days) (p=0.000034). Multivariate analysis showed that post-nasal drip symptoms are independent prolonged factors of cough duration.
Post-nasal drip symptoms may affect cough control in patients with cough-variant and cough-predominant asthma.
背景/目的：本研究旨在阐明变异性咳嗽和以咳嗽为主要表现的哮喘患者中，过敏性鼻炎和后鼻滴注症状的意义。
我们对 2012 年 6 月至 2015 年 7 月期间首次到日本中岛诊所就诊的 91 例变异性咳嗽或以咳嗽为主的哮喘患者进行了回顾性分析。
58 例（63.7%）患者有后鼻滴注症状。有后鼻滴注症状的患者（19.5±8.3 天）咳嗽消失时间明显长于无后鼻滴注症状的患者（11.0±4.8 天）（p=0.000034）。多变量分析表明，后鼻滴注症状是咳嗽持续时间的独立延长因素。
后鼻滴注症状可能影响变异性咳嗽和以咳嗽为主要表现的哮喘患者的咳嗽控制。
