Park Hee Jae, Park Hai-Jin
Department of Dermatology, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Ann Dermatol. 2020 Feb;32(1):74-76. doi: 10.5021/ad.2020.32.1.74. Epub 2019 Dec 27.
Onychopapilloma is a rare benign neoplasm of the nail bed and the distal matrix. It is the most common cause of monodactylous localized longitudinal erythronychia. Splinter hemorrhage, onycholysis or distal splitting are usually accompanied due to the subungual keratotic growth located in the corresponding linear streak. A 50-year-old female was referred for the evaluation of 1-mm width of erythematous band on the left thumbnail. Distal onycholysis and splinter hemorrhages were seen along the streak with a thread-like horny papule beneath the edge of the nail plate. On histopathologic examination, papillomatosis and acanthosis were observed in the distal nail bed epithelium. The upper layers of the nail bed epithelium showed matrix metaplasia. The nail plate specimen revealed subungual hyperkeratosis with focal hemorrhage. The histopathological findings confirmed the clinical diagnosis of onychopapilloma. Herein, we report a rare case of onychopapilloma presenting as a longitudinal erythronychia.
甲乳头状瘤是一种罕见的甲床和远端甲母质良性肿瘤。它是单指局限性纵向红甲最常见的病因。由于位于相应线性条纹处的甲下角化性生长,通常伴有裂片形出血、甲剥离或远端裂开。一名50岁女性因左拇指指甲出现1毫米宽的红斑带前来评估。沿条纹可见远端甲剥离和裂片形出血,在甲板边缘下方有一条丝状角质丘疹。组织病理学检查显示,远端甲床上皮出现乳头瘤病和棘层肥厚。甲床上皮上层显示甲母质化生。甲板标本显示甲下角化过度伴局灶性出血。组织病理学结果证实了甲乳头状瘤的临床诊断。在此,我们报告一例罕见的以纵向红甲表现的甲乳头状瘤病例。