Prabhakar Orsu, Bhuvaneswari Mylipilli
Department of Pharmacology, GITAM Institute of Pharmacy, Visakhapatnam, Andhra Pradesh, India.
Tzu Chi Med J. 2020 Oct 5;33(2):135-145. doi: 10.4103/tcmj.tcmj_86_20. eCollection 2021 Apr-Jun.
Nonalcoholic fatty liver disease (NAFLD) is considered as the hepatic evidence of insulin resistance which is the hallmark of type 2 diabetes. NAFLD is considered as the risk factor for developing type 2 diabetes and has a high frequency of occurrence in those with existing type 2 diabetes. Compared with patients with only NAFLD or type 2 diabetes, these patients show a poor metabolic profile and increase mortality. Hence, effective treatment strategies are necessary. Here, we review the role of diet and lifestyle modification in the management of NAFLD and type 2 diabetes. Based on the available studies, it has been shown that the addition of any kind of physical activity or exercise is beneficial for patients with both NAFLD and type 2 diabetes. Proper dietary management leads to weight loss are also effective in improving metabolic parameters in patients with both NAFLD and type 2 diabetes. In conclusion, it is clear that increasing physical activity or exercise is effective in improving metabolic parameters in patients who are suffering with both NAFLD and type 2 diabetes.
非酒精性脂肪性肝病(NAFLD)被认为是胰岛素抵抗的肝脏表现,而胰岛素抵抗是2型糖尿病的标志。NAFLD被视为发生2型糖尿病的危险因素,并且在已患2型糖尿病的人群中发生率很高。与仅患有NAFLD或2型糖尿病的患者相比,这些患者的代谢状况较差且死亡率增加。因此,需要有效的治疗策略。在此,我们综述饮食和生活方式改变在NAFLD和2型糖尿病管理中的作用。基于现有研究,已表明增加任何形式的体力活动或运动对患有NAFLD和2型糖尿病的患者均有益。适当的饮食管理导致体重减轻,对患有NAFLD和2型糖尿病的患者改善代谢参数也有效。总之,显然增加体力活动或运动对同时患有NAFLD和2型糖尿病的患者改善代谢参数是有效的。