Department of Thoracic Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China.
Department of Thoracic Surgery, Meihekou City Central Hospital, Meihekou, Jilin Province, China.
Endocrine. 2019 Apr;64(1):38-42. doi: 10.1007/s12020-019-01875-3. Epub 2019 Feb 25.
Primary hyperparathyroidism (PHPT) is a common endocrine disorder and is usually diagnosed in adults. PHPT due to ectopic parathyroid adenoma in adolescents is rare.
We describe the case of a 15-year-old boy with PHPT due to ectopic parathyroid adenoma. A review of the literature of PHPT in adolescents was performed, focusing on etiology, clinical presentation, preoperative localization methods, pathology, and treatment.
The patient was successfully treated with surgery and was followed up for 5 years with no signs or symptoms of hyperparathyroidism. By reviewing the literature, only seven cases of PHPT associated with ectopic parathyroid lesions in adolescents have been reported. Parathyroidectomy is the only known curative treatment. Accurate preoperative localization of the target lesion is critical.
This study should raise awareness of the diagnosis and treatment of PHPT due to ectopic parathyroid adenoma/carcinoma in adolescents.
原发性甲状旁腺功能亢进症（PHPT）是一种常见的内分泌疾病，通常在成人中诊断。青少年异位甲状旁腺腺瘤引起的 PHPT 较为罕见。
我们描述了一例 15 岁男孩因异位甲状旁腺腺瘤引起的 PHPT。对青少年 PHPT 的文献进行了回顾，重点关注病因、临床表现、术前定位方法、病理和治疗。
患者成功接受手术治疗，随访 5 年无甲状旁腺功能亢进的迹象或症状。通过文献回顾，仅报道了 7 例与青少年异位甲状旁腺病变相关的 PHPT。甲状旁腺切除术是唯一已知的治愈性治疗方法。准确的术前靶病变定位至关重要。
本研究应提高对青少年异位甲状旁腺腺瘤/癌引起的 PHPT 的诊断和治疗的认识。
