College of Chemistry, Nanchang University, Nanchang 330031, China.
Anal Methods. 2021 May 20;13(19):2229-2237. doi: 10.1039/d1ay00495f.
In this paper, a new Co3O4-Ni nanocomposite-modified glassy carbon electrode (Co3O4-NiNPs/GCE) was successfully constructed and used to detect glucose and hydrogen peroxide (H2O2). The morphologies and structures of the Co3O4 and Co3O4-Ni nanocomposites were characterized via transmission electron microscopy (TEM), scanning electron microscopy (SEM), and X-ray diffraction (XRD). The construction process of the modified electrode was characterized via electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) techniques. Co3O4-NiNPs/GCE shows more excellent electrocatalytic activity for the detection of glucose and H2O2 compared with Co3O4/GCE and NiNPs/GCE. The amperometric i-t method was used for the quantitative analysis of glucose and H2O2. The plots of current difference versus concentration of glucose and H2O2 were linear in the range of 0.3-550 μM and 0.5-89 μM, respectively. The corresponding limits of detection (LODs) were 0.086 μM and 0.23 μM for glucose and H2O2, respectively. This recommended sensor was successfully applied for the quantitative analysis of glucose in fruit and H2O2 in water samples.
本文构建了一种新型 Co3O4-Ni 纳米复合材料修饰玻碳电极（Co3O4-NiNPs/GCE），并用于检测葡萄糖和过氧化氢（H2O2）。通过透射电子显微镜（TEM）、扫描电子显微镜（SEM）和 X 射线衍射（XRD）对 Co3O4 和 Co3O4-Ni 纳米复合材料的形貌和结构进行了表征。通过电化学阻抗谱（EIS）和循环伏安法（CV）技术对修饰电极的构建过程进行了表征。与 Co3O4/GCE 和 NiNPs/GCE 相比，Co3O4-NiNPs/GCE 对葡萄糖和 H2O2 的检测表现出更优异的电催化活性。采用安培电流法对葡萄糖和 H2O2 进行定量分析。电流差与葡萄糖和 H2O2 浓度的关系图在 0.3-550 μM 和 0.5-89 μM 范围内呈线性关系。葡萄糖和 H2O2 的相应检测限（LOD）分别为 0.086 μM 和 0.23 μM。该推荐传感器成功应用于水果中葡萄糖和水样中 H2O2 的定量分析。
