Bitsch M, Johansen C, Wennevold A, Osler M
Department of Gynecology and Obstetrics, Rigshospitalet, Copenhagen, Denmark.
Eur J Obstet Gynecol Reprod Biol. 1988 May;28(1):69-74. doi: 10.1016/0028-2243(88)90061-5.
Two cases of successfully managed Eisenmenger's syndrome during pregnancy are reported. A women suffering from Eisenmenger's syndrome who becomes pregnant should be advised to have her pregnancy terminated. On the basis of the available literature and our own experiences we suggest the following plan, if a woman, despite medical advice, chooses to continue her pregnancy: admission to hospital at approximately 25 weeks of gestation; bed rest during the remaining period of pregnancy; oxygen face-mask during episodes of dyspnoea; determination of serial blood gases to detect changes in the shunt flow. At the onset of labour, arterial and epidural catheters should be inserted, a fall in blood pressure should immediately be counteracted by the administration of norepinephrine and loss of blood by transfusion. The patient should remain in hospital for 7-14 days after delivery.
报告了两例孕期成功治疗艾森曼格综合征的病例。患有艾森曼格综合征的女性怀孕后，应建议其终止妊娠。根据现有文献及我们自己的经验，我们建议如下方案：若一名女性不顾医学建议而选择继续妊娠，应在妊娠约25周时入院；孕期剩余时间卧床休息；呼吸困难发作时使用面罩吸氧；定期测定血气以检测分流血流的变化。分娩开始时，应插入动脉导管和硬膜外导管，血压下降时应立即给予去甲肾上腺素进行对抗，失血时应进行输血。患者产后应住院7 - 14天。
