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微量营养素与呼吸道感染:生物学依据与临床评估现状。

Micronutrients and respiratory infections: the biological rationale and current state of clinical evaluation.

机构信息

Adult Critical Care Unit, Newham University Hospital, Barts Health NHS Trust, London, UK.

Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.

出版信息

Br J Hosp Med (Lond). 2021 Apr 2;82(4):1-8. doi: 10.12968/hmed.2020.0730. Epub 2021 Apr 27.

DOI:10.12968/hmed.2020.0730
PMID:33914636
Abstract

A range of nutrients has been studied or proposed for use in preventing respiratory tract infections and reducing their severity. This article gives a narrative review of the existing literature, biological rationales and current state of clinical evaluation for micronutrient therapies. The importance of vitamin A, the B vitamins, vitamin C, vitamin D, eicosapentaenoic acid, vitamin E, selenium, zinc and a range of combination therapies are discussed, looking at their effects on reducing rates of infection, reducing severity of infection and improved recovery from infection. Further discussion regarding the level of evidence required for nutritional interventions is included.

摘要

已经有一系列营养素被研究或提议用于预防呼吸道感染并减轻其严重程度。本文对现有文献、生物学原理和临床评估的现状进行了叙述性综述,讨论了微量营养素疗法的重要性,包括维生素 A、B 族维生素、维生素 C、维生素 D、二十碳五烯酸、维生素 E、硒、锌以及一系列联合疗法,着眼于它们在降低感染率、减轻感染严重程度和促进感染康复方面的效果。此外,还讨论了营养干预所需的证据水平。

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