Mehdiyev Turkhan, Zimmermann Robert
Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Innsbruck, Anichstrasse 35, Innsbruck, Austria.
Wounds. 2021 Feb;33(2):E14-E16.
Pyoderma gangrenosum (PG) is a rare, neutrophilic dermatosis that can be triggered after minor trauma or surgery and mimics a fulminating infection. It is commonly associated with a systemic disease, such as inflammatory bowel disease, metabolic syndrome, rheumatologic or hematological disorders, and malignancies. The typical clinical appearance is hemorrhagic nodules, which rapidly progress into extremely painful, irregular, red to violaceous ulceration with undermined border and purulent necrotic bases. The treatment of PG is nonsurgical. Unnecessary surgical procedures may incite a pathergic response, worsening the disease dramatically and potentially resulting in a limb amputation.
A report of PG, originally misdiagnosed as an infection after a carpal tunnel release, is presented.
This case emphasizes the importance of early recognition of PG to provide a timely diagnosis and avoid unnecessary surgeries, which can result in devastating consequences.
坏疽性脓皮病(PG)是一种罕见的嗜中性皮病,可在轻微创伤或手术后引发,类似暴发性感染。它通常与全身性疾病相关,如炎症性肠病、代谢综合征、风湿性或血液系统疾病以及恶性肿瘤。典型的临床表现为出血性结节,迅速发展为极其疼痛、不规则、红色至紫红色的溃疡,边界呈潜行性,底部为脓性坏死。PG的治疗是非手术性的。不必要的手术操作可能引发同形反应,使病情急剧恶化,甚至可能导致肢体截肢。
本文报告了一例PG,最初在腕管松解术后被误诊为感染。
该病例强调了早期识别PG以提供及时诊断并避免不必要手术的重要性,否则可能导致灾难性后果。