Bansal Aditi, Singla Ankur, Singh Aminder, Kaur Sukhjot
Department of Dermatology, Venereology and Leprology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Department of Intern in Department of dermatology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Indian Dermatol Online J. 2022 Mar 3;13(2):244-247. doi: 10.4103/idoj.idoj_274_21. eCollection 2022 Mar-Apr.
Pyoderma gangrenosum is a rare, chronic neutrophilic dermatosis of unknown etiology. The classical clinical feature of pyoderma gangrenosum is a pustule or plaque that rapidly progresses to a painful, necrotic ulcer with undermined violaceous margins. Pyoderma gangrenosum may be associated with underlying inflammatory bowel diseases, hematological malignancies, or rheumatologic disorders in 50-70% of the cases. The visceral involvement by pyoderma gangrenosum is rare. Sterile neutrophilic infiltrates in organs other than the skin are uncommon systemic manifestations of neutrophilic dermatoses, but have occasionally been reported. We report a case of a 38-year-old female with pyoderma gangrenosum and visceral involvement manifesting as splenic abscess.
坏疽性脓皮病是一种病因不明的罕见慢性嗜中性皮肤病。坏疽性脓皮病的典型临床特征是脓疱或斑块,迅速发展为疼痛性坏死性溃疡,边缘呈紫红色且有潜行。在50%至70%的病例中,坏疽性脓皮病可能与潜在的炎症性肠病、血液系统恶性肿瘤或风湿性疾病有关。坏疽性脓皮病累及内脏罕见。皮肤以外器官出现无菌性嗜中性粒细胞浸润是嗜中性皮肤病罕见的全身表现,但偶尔也有报道。我们报告一例38岁女性坏疽性脓皮病合并内脏受累表现为脾脓肿的病例。