Lunn G, Sansone E B
Environmental Control and Research Program, National Cancer Institute-Frederick Cancer Research Facility, MD 21701-1013.
Food Chem Toxicol. 1988 May;26(5):481-4. doi: 10.1016/0278-6915(88)90061-0.
Spills of N-methyl-N-nitrosourea, N-ethyl-N-nitrosourea, N-methyl-N-nitrosourethane and N-ethyl-N-nitrosourethane can be decontaminated using a mixture of ethanol and saturated aqueous sodium bicarbonate solution. Spills of N-methyl-N-nitroso-p-toluenesulphonamide, N-methyl-N'-nitro-N-nitrosoguanidine and N-ethyl-N'-nitro-N-nitrosoguanidine can be decontaminated with a solution of sulphamic acid in 2 M-hydrochloric acid. In all cases the nitrosamides are completely destroyed and only non-mutagenic reaction mixtures are produced.
N-甲基-N-亚硝基脲、N-乙基-N-亚硝基脲、N-甲基-N-亚硝基氨基甲酸乙酯和N-乙基-N-亚硝基氨基甲酸乙酯的泄漏物可用乙醇和饱和碳酸氢钠水溶液的混合物进行去污处理。N-甲基-N-亚硝基对甲苯磺酰胺、N-甲基-N'-硝基-N-亚硝基胍和N-乙基-N'-硝基-N-亚硝基胍的泄漏物可用氨基磺酸在2M盐酸中的溶液进行去污处理。在所有情况下，亚硝酰胺均被完全破坏，仅产生无致突变性的反应混合物。
