School of Sport and Exercise Science, University of Northern Colorado, Campus Box 39, Greeley, CO, 80639, USA; School of Integrative Physiology & Athletic Training, University of Montana, 32 Campus Drive, Missoula, MT, 59812, USA.
School of Sport and Exercise Science, University of Northern Colorado, Campus Box 39, Greeley, CO, 80639, USA; University of Northern Colorado Cancer Rehabilitation Institute, Campus Box 6, Greeley, CO, 80639, USA.
Gait Posture. 2021 Jun;87:136-142. doi: 10.1016/j.gaitpost.2021.04.013. Epub 2021 Apr 20.
Cancer and cancer treatments negatively affect somatosensory, vestibular, and visual inputs that regulate postural stability and balance, increasing the risk of falling. Exercise training has been shown to mitigate other negative side effects of cancer treatments, such as reducing peripheral neuropathy.
How does 12 weeks of supervised exercise training influence postural stability in cancer survivors who receive chemotherapy?
Postural stability of cancer survivors (n = 25; mass = 79.0 ± 22.6 kg; height = 1.66 ± 0.08 m; age = 61 ± 10 years) receiving chemotherapy was assessed prior to and following a 12-week individualized exercise training program by quantifying changes in center of pressure data. A series of 2-factor (pre/post x condition) analysis of variance with repeated measures were used to identify differences between conditions and pre- and post- training program on time and frequency domain measures.
Mediolateral root mean square excursion (p = 0.040; es = 0.20) and resultant mean frequency (p = 0.044; es = 0.29) of the center of pressure trajectory were found to be significantly different between pre- and post-training program. Further, participants dealt better with perturbations after completing the training program by reducing mediolateral root mean square excursion and 95 % confidence ellipse when visual stimulus was removed.
Supervised exercise training in cancer patients undergoing chemotherapy improves postural stability in the mediolateral direction. Given that mediolateral movement of the center of pressure has previously been associated with fallers in other populations, exercise training during cancer treatments may be beneficial.
癌症和癌症治疗会对调节姿势稳定性和平衡的躯体感觉、前庭和视觉输入产生负面影响，增加跌倒的风险。运动训练已被证明可以减轻癌症治疗的其他负面副作用，例如减少周围神经病变。
12 周的监督运动训练如何影响接受化疗的癌症幸存者的姿势稳定性？
在接受化疗的癌症幸存者（n = 25；体重 = 79.0 ± 22.6 kg；身高 = 1.66 ± 0.08 m；年龄 = 61 ± 10 岁）接受 12 周个体化运动训练计划之前和之后，通过量化压力中心数据的变化来评估姿势稳定性。使用具有重复测量的 2 因素（预/后 x 条件）方差分析来确定条件之间以及训练计划前后在时间和频域测量上的差异。
发现压力中心轨迹的中-侧根均方根偏移（p = 0.040；es = 0.20）和均方根频率（p = 0.044；es = 0.29）在训练计划前后有显著差异。此外，参与者在完成训练计划后通过减少中-侧根均方根偏移和去除视觉刺激时 95%置信椭圆来更好地应对扰动。
在接受化疗的癌症患者中进行监督运动训练可改善中-侧方向的姿势稳定性。鉴于压力中心的中-侧运动先前与其他人群中的跌倒者有关，因此在癌症治疗期间进行运动训练可能是有益的。
