Liu Y, Zheng G Y, Shan Y Q, Chen T
Department of Ophthalmology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Zhonghua Yan Ke Za Zhi. 2021 May 11;57(5):358-365. doi: 10.3760/cma.j.cn112142-20200621-00412.
To evaluate the visual quality after phacoemulsification and implantation of a rotational asymmetric refractive intraocular lens in patients with high myopia and cataract. A retrospective cohort study. Sixty-two patients (92 eyes) of the First Affiliated Hospital of Zhengzhou University from June 2017 to December 2019 were evaluated after phacoemulsification and implantation of a rotational asymmetric refractive intraocular lens (LS-313 MF30). According to the axial length, the participants were allocated to either a control group or a high myopia group. Among the 33 patients (46 eyes) in the control group, the axial length was shorter than 26 mm; among the 29 patients (46 eyes) in the high myopia group, the axial length was more than 26 mm. The high myopia group was further divided into two subgroups. The super high myopia subgroup included 12 patients (18 eyes), and the axial length was ≥30 mm; the high myopia subgroup consisted of 17 patients (28 eyes), and the axial length was<30 mm and ≥26 mm. Uncorrected distance visual acuity, uncorrected intermediate visual acuity and uncorrected near visual acuity were recorded after surgery. The follow-up time was more than 6 months. At the end of the follow-up, patients' contrast sensitivity (CS), reading acuity, reading speed and visual quality questionnaire results were assessed. The main statistical methods were two-way repeated measures analysis of variance, independent sample -test, one-way analysis of variance and Kruskal-Wallis test. There were no significant differences in gender distribution, age, or follow-up time between the control and high myopia groups, the control and high myopia subgroup, or the super high myopia subgroup (all >0.05). At the end of the follow-up, the uncorrected distance, intermediate and near visual acuity of the super high myopia subgroup was 0.07±0.11, 0.34±0.08 and 0.20±0.09, respectively. The difference in postoperative visual acuity was not statistically significant (all >0.05). The CS and CS with glare of the high myopia group (3 cpd: 1.48±0.18, 1.42±0.16; 6 cpd: 1.75±0.18, 1.76±0.15; 12 cpd: 1.44±0.24, 1.43±0.19; 18 cpd: 0.90±0.23, 0.85±0.20) were significantly different from the control group (3 cpd: 1.66±0.18, 1.62±0.16; 6 cpd: 1.88±0.14, 1.85±0.11; 12 cpd: 1.54±0.18, 1.53±0.14; 18 cpd: 1.06±0.18, 1.01±0.15) (<0.05), except at 12 cpd (=0.05). The CS and CS with glare of the super high myopia subgroup (3 cpd: 1.39±0.21, 1.31±0.13; 6 cpd: 1.66±0.16, 1.64±0.12; 12 cpd: 1.32±0.23, 1.31±0.18; 18 cpd: 0.75±0.16, 0.73±0.15) were worst (all <0.05). A significant difference between the high myopia subgroup and the control group was only found at 3 cpd (1.53±0.13 . 1.66±0.18, 1.50±0.13 . 1.62±0.16; both <0.05). The reading acuity and reading speed of the super high myopia subgroup were lower than the high myopia subgroup and the control group, while the differences were not statistically significant (all >0.05). The questionnaire survey showed that there was no significant difference in the proportion of glare and halo between the two subgroups and the control group (both >0.05). No patients reported dissatisfaction. The rate of glasses independents was 11/12 in the super high myopia subgroup, 15/17 in the high myopia subgroup and 31/33 in the control group, with no significant difference (>0.05). The rotational asymmetric refractive intraocular lens is suitable for patients with high myopia and cataract, and has good far and near vision after operation. However, it could result in relatively low CS for super high myopia patients, so rigorous preoperative examination must be done. .
评估高度近视合并白内障患者行超声乳化白内障吸除术联合植入旋转不对称屈光性人工晶状体后的视觉质量。一项回顾性队列研究。对2017年6月至2019年12月在郑州大学第一附属医院行超声乳化白内障吸除术联合植入旋转不对称屈光性人工晶状体(LS-313 MF30)的62例患者(92只眼)进行评估。根据眼轴长度,将参与者分为对照组和高度近视组。对照组33例患者(46只眼),眼轴长度短于26mm;高度近视组29例患者(46只眼),眼轴长度大于26mm。高度近视组进一步分为两个亚组。超高度近视亚组包括12例患者(18只眼),眼轴长度≥30mm;高度近视亚组由17例患者(28只眼)组成,眼轴长度<30mm且≥26mm。记录术后裸眼远视力、裸眼中视力和裸眼近视力。随访时间超过6个月。随访结束时,评估患者的对比敏感度(CS)、阅读视力、阅读速度和视觉质量问卷结果。主要统计方法为双向重复测量方差分析、独立样本t检验、单因素方差分析和Kruskal-Wallis检验。对照组与高度近视组、对照组与高度近视亚组、超高度近视亚组之间在性别分布、年龄或随访时间上均无显著差异(均>0.05)。随访结束时,超高度近视亚组的裸眼远视力、中视力和近视力分别为0.07±0.11、0.34±0.08和0.20±0.09。术后视力差异无统计学意义(均>0.05)。高度近视组的CS及眩光下CS(3cpd:1.48±0.18,1.42±0.16;6cpd:1.75±0.18,1.76±0.15;12cpd:1.44±0.24,1.43±0.19;18cpd:0.90±0.23,0.85±0.20)与对照组(3cpd:1.66±0.18,1.62±0.16;6cpd:1.88±0.14,1.85±0.11;12cpd:1.54±0.18,1.53±0.14;18cpd:1.06±0.18,1.01±0.15)相比有显著差异(均<0.05),12cpd时除外(P=0.05)。超高度近视亚组的CS及眩光下CS(3cpd:1.39±0.21,1.31±0.13;6cpd:1.66±0.16,1.64±0.12;12cpd:1.32±0.23,1.31±0.18;18cpd:0.75±0.16,0.73±0.15)最差(均<0.05)。高度近视亚组与对照组仅在3cpd时有显著差异(1.53±0.13 vs 1.66±0.18,1.50±0.13 vs 1.62±0.16;均<0.05)。超高度近视亚组的阅读视力和阅读速度低于高度近视亚组和对照组,但差异无统计学意义(均>0.05)。问卷调查显示,两个亚组与对照组之间在眩光和光晕比例上无显著差异(均>0.05)。无患者表示不满意。超高度近视亚组、高度近视亚组和对照组的脱镜率分别为11/12、15/17和31/33,无显著差异(>0.05)。旋转不对称屈光性人工晶状体适用于高度近视合并白内障患者,术后远近视力良好。然而,对于超高度近视患者,其CS可能相对较低,因此必须进行严格的术前检查。