Zohdy Marwa, Cazzaniga Simone, Nievergelt Helga, Blum Roland, Suter Valérie G A, Feldmeyer Laurence, Beltraminelli Helmut
Department of Dermatology, Inselspital Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.
Department of Dermatology, Andrology and STDs, Mansoura University Hospitals, Mansoura University, Mansoura 35516, Egypt.
Dermatopathology (Basel). 2021 Apr 1;8(2):84-88. doi: 10.3390/dermatopathology8020013.
Oral lichen planus (OLP) and oral lichenoid lesions (OLL) can both present with histological dysplasia. Despite the presence of WHO-defined criteria for the evaluation of epithelial dysplasia, its assessment is frequently subjective (inter-observer variability). The lack of reproducibility in the evaluation of dysplasia is even more complex in the presence of a lichenoid inflammation. We evaluated dysplasia in 112 oral biopsies with lichenoid inflammation in order to study the inter-observer and the intra-observer variability.
口腔扁平苔藓（OLP）和口腔苔藓样病变（OLL）均可出现组织学发育异常。尽管存在世界卫生组织定义的上皮发育异常评估标准，但其评估往往具有主观性（观察者间差异）。在存在苔藓样炎症的情况下，发育异常评估缺乏可重复性的问题更为复杂。我们对112例伴有苔藓样炎症的口腔活检组织中的发育异常进行了评估，以研究观察者间和观察者内的差异。
