Hansen Rikke Middelhede, Krogh Klaus, Sundby Joan, Krassioukov Andrei, Hagen Ellen Merete
Spinal Cord Injury Centre of Western Denmark, Department of Neurology, Regional Hospital, DK-8800 Viborg, Denmark.
Department of Hepatology and Gastroenterology, Aarhus University Hospital, DK-8200 Aarhus, Denmark.
J Clin Med. 2021 Apr 1;10(7):1417. doi: 10.3390/jcm10071417.
Postprandial hypotension (PPH) is defined as a fall of ≥20 mmHg in systolic blood pressure (SBP) or a SBP of <90 mmHg after having been >100 mmHg before the meal within two hours after a meal. The prevalence of PPH among persons with spinal cord injury (SCI) is unknown. Ambulatory blood pressure measurement was performed in 158 persons with SCI, 109 men, median age was 59.1 years (min.:13.2; max.: 86.2). In total, 78 persons (49.4%) had PPH after 114 out of 449 meals (25.4%). The median change in SBP during PPH was -28 mmHg (min.: -87; max.: -15 mmHg) and 96% of the PPH episodes were asymptomatic. The occurrence of PPH was correlated to older age ( = 0.001), level of injury ( = 0.023), and complete SCI ( = 0.000), but not, gender or time since injury. Further studies are needed to elucidate if PPH contributes to the increased cardiovascular mortality in the SCI population.
餐后低血压（PPH）定义为餐后两小时内收缩压（SBP）下降≥20 mmHg或SBP<90 mmHg，且餐前SBP>100 mmHg。脊髓损伤（SCI）患者中PPH的患病率尚不清楚。对158例SCI患者进行了动态血压测量，其中男性109例，中位年龄为59.1岁（最小：13.2岁；最大：86.2岁）。总共449餐中有114餐（25.4%）后78例患者（49.4%）出现PPH。PPH期间SBP的中位变化为-28 mmHg（最小：-87 mmHg；最大：-15 mmHg），96%的PPH发作无症状。PPH的发生与年龄较大（P = 0.001）、损伤水平（P = 0.023）和完全性SCI（P = 0.000）相关，但与性别或受伤时间无关。需要进一步研究以阐明PPH是否导致SCI人群心血管死亡率增加。
