This study aimed to investigate the risk factors for and the outcomes of patients with candidemia caused by non-. Candidemia patients treated at Siriraj Hospital (Bangkok, Thailand) during January 2016 to December 2017 were enrolled. A total of 156 patients (mean age: 65 years, 56.4% male) were included. The most prevalent underlying conditions were diabetes (32.1%), chronic cardiac disease (28.2%), chronic kidney disease (26.9%), and hematologic malignancies (21.2%). species isolated from patient blood were (49.4%), (28.8%), (16.7%), and (5.1%). Fluconazole resistance was significantly increased in (37.8%). No independent risk factors were associated with patients with non- candidemia compared to those with candidemia. There was no significant difference in mortality between patients with non- candidemia and patients with candidemia (OR: 1.35, 95% CI: 0.64-2.85). When compared with candidemia, multivariate analysis revealed chronic liver disease (OR: 11.39, 95% CI: 1.38-94.02), neutropenia (OR: 4.31, 95% CI: 1.34-13.87), and male gender (OR: 2.34, 95% CI: 1.04-5.29) to be independent risk factors for candidemia. The observed high resistance of to fluconazole indicates that fluconazole should not be used for empirical antifungal treatment in these patients.