Näslund I, Hallgren P, Sjöström L
Department of Surgery, Orebro Medical Center Hospital, Sweden.
Int J Obes. 1988;12(3):191-7.
Fifty-one morbidly obese women were randomized and operated upon with either gastroplasty or gastric bypass. The patients were studied preoperatively and 12 months after surgery. The weight loss was significantly larger after gastric bypass. Fat cell weight was determined from subcutaneous fat biopsies of the epigastric, hypogastric, femoral and gluteal regions. Intra-abdominal biopsies were also taken during the operation. Fat cell weight decreased significantly in all subcutaneous regions. Fat cell number, derived from calculated body fat and measured mean subcutaneous fat cell weight, decreased significantly in both treatment groups.
51名病态肥胖女性被随机分组，接受胃成形术或胃旁路手术。对患者在术前及术后12个月进行了研究。胃旁路手术后体重减轻更为显著。通过对上腹部、下腹部、股部和臀部皮下脂肪活检来测定脂肪细胞重量。手术期间也采集了腹部内活检样本。所有皮下区域的脂肪细胞重量均显著下降。根据计算出的体脂和测量的平均皮下脂肪细胞重量得出的脂肪细胞数量，在两个治疗组中均显著减少。
