Näslund I, Beckman K W
Scand J Gastroenterol. 1987 Mar;22(2):193-201. doi: 10.3109/00365528708991879.
Fifty-seven morbidly obese patients were randomized into two surgical treatment groups, gastric bypass (n = 29) and gastroplasty (n = 28). Studies of the gastric emptying with radionuclide-labelled food were performed preoperatively (12 patients) and postoperatively at 2 months (28 patients) and 12 months (49 patients). Pouch emptying after gastric bypass was slower at 2 months than at 12 months. After gastroplasty the emptying rate was the same at 2 and 12 months and the same as that of gastric bypass at 12 months. A statistically significant correlation between stoma diameter and emptying rate was seen 1 year after gastroplasty but not after gastric bypass. No correlation between emptying rate and weight loss was shown in either group. Differences in the mechanisms of action between these two methods are apparent and are discussed.
57例病态肥胖患者被随机分为两个手术治疗组，即胃旁路手术组（n = 29）和胃成形术组（n = 28）。术前（12例患者）以及术后2个月（28例患者）和12个月（49例患者）采用放射性核素标记食物对胃排空情况进行了研究。胃旁路手术后2个月时的胃囊排空比12个月时慢。胃成形术后2个月和12个月时的排空率相同，且与胃旁路手术12个月时的排空率相同。胃成形术后1年可见吻合口直径与排空率之间存在统计学显著相关性，而胃旁路手术后则未发现。两组均未显示排空率与体重减轻之间存在相关性。这两种方法的作用机制差异明显，并对此进行了讨论。
