Kvist H, Chowdhury B, Sjöström L, Tylén U, Cederblad A
Department of Diagnostic Radiology, University of Göteborg, Sahlgren Hospital, Sweden.
Int J Obes. 1988;12(3):249-66.
Seventeen healthy male volunteers with weights ranging from 54 to 145 kg were examined with a Philips Tomoscan 310. The upper attenuation limit of adipose tissue was determined to be -30 HU. The lower attenuation limit was set to -190 HU. Regional and total adipose tissue volumes were calculated from the adipose tissue areas of 22 scans and from the distances between these scans. Three different mathematical formulas were used, which all gave similar results. The adipose tissue area of several trunk scans, as well as the elbow, showed very high correlations (r greater than 0.96) versus the volume determinations based on 22 scans. The visceral adipose tissue area of scan L2-L3 showed a higher correlation (r = 0.986) than any other single scan versus the visceral adipose tissue volume. Total adipose tissue volume determinations with ten selected scans correlated very closely with the results obtained from 22 scans (r = 0.997). The adipose tissue volume of the head and neck region was 1.9 +/- 1.0 per cent of the total volume. Corresponding figures for other regions were: arms 6.8 +/- 1.0 per cent, legs 29.0 +/- 7.3 per cent, subcutaneous part of the trunk 41.4 +/- 7.4 per cent and the visceral region 20.9 +/- 7.0 per cent. With greater total adipose tissue volumes the percentage of the subcutaneous adipose tissue of the trunk increased (r = 0.686; P less than 0.005). There was a very strong negative relationship between the fractional amount of adipose tissue in the legs and in the trunk (r = 0.993, P less than 0.001). The potassium contents of fat-free mass and lean body mass were deduced to be 64.7 and 71.0 mmol/kg, respectively. These calculations were based on adipose tissue volume determinations by computed tomography, on 40K measurements and on the assumption that the volume proportions of fat, water and protein in adipose tissue were 85:13.7:1.3. By using computed tomography (CT) as a standard an optimal weight (W) for height (H) index was constructed by using an iterative correlation technique. The optimal index, i.e. highest correlation and lowest error versus ATCT was found for W/H0.9.
17名体重在54至145千克之间的健康男性志愿者接受了飞利浦Tomoscan 310的检查。确定脂肪组织的上部衰减极限为-30 HU，下部衰减极限设定为-190 HU。根据22次扫描的脂肪组织面积以及这些扫描之间的距离计算局部和总脂肪组织体积。使用了三种不同的数学公式，结果都相似。几次躯干扫描以及肘部的脂肪组织面积与基于22次扫描的体积测定显示出非常高的相关性（r大于0.96）。扫描L2-L3的内脏脂肪组织面积与内脏脂肪组织体积的相关性高于任何其他单次扫描（r = 0.986）。用十次选定扫描进行的总脂肪组织体积测定与22次扫描得到的结果非常紧密相关（r = 0.997）。头颈部区域的脂肪组织体积占总体积的1.9±1.0%。其他区域的相应数字为：手臂6.8±1.0%，腿部29.0±7.3%，躯干皮下部分41.4±7.4%，内脏区域20.9±7.0%。随着总脂肪组织体积增加，躯干皮下脂肪组织的百分比增加（r = 0.686；P小于0.005）。腿部和躯干中脂肪组织的分数之间存在非常强的负相关关系（r = 0.993，P小于0.001）。无脂肪质量和瘦体重的钾含量分别推断为64.7和71.0 mmol/kg。这些计算基于计算机断层扫描测定的脂肪组织体积、40K测量以及脂肪组织中脂肪、水和蛋白质的体积比例为85:13.7:1.3的假设。通过使用计算机断层扫描（CT）作为标准，采用迭代相关技术构建了身高（H）的最佳体重（W）指数。发现W/H0.9的最佳指数，即与ATCT的相关性最高且误差最低。
