Departamento de Bioquímica, Biología Molecular y Fisiología, Facultad de Ciencias de la Salud, GIR de Ejercicio Físico y Envejecimiento, Campus Universitario "Los Pajaritos", Universidad de Valladolid, 42004 Soria, Spain.
Departamento de Anatomía y Radiología, Facultad de Ciencias de la Salud, GIR de Ejercicio Físico y Envejecimiento, Campus Universitario "Los Pajaritos", Universidad de Valladolid, 42004 Soria, Spain.
Int J Environ Res Public Health. 2021 Apr 9;18(8):3937. doi: 10.3390/ijerph18083937.
The work of health professionals in hospital emergency rooms is highly demanding due to the decisions they must take. In the present study, we consider assessing stress response in emergency health workers, measuring related biomarkers such as cortisol, dehydroepiandrosterone (DHEA) and salivary α-amylase during the whole working day.
An analytical, descriptive and cross-sectional study was carried out. The study was conducted in the emergency rooms of two public hospitals. Ninety-seven professionals participated, 45 corresponding to one hospital and 52 to the other. Four salivary samples were obtained according to circadian rhythms: at 8:00, 12:00, 15:00 and 00:00 h/24 h. The data were subsequently analyzed.
Cortisol levels decreased throughout the working day, with minimum values being at 24 h. A similar pattern was observed in DHEA. The α-amylase levels increased throughout the working day, reaching its peak at 15:00 h, and decreasing at 24 h, compared to the data from the rest of the working day.
Since reference/baseline values are not presented, this work is focused on a stress situation experienced during one regular working day in emergency rooms with no extreme situations. In this context, stress, measured through cortisol and α-amylase, is present in emergency room doctors and nurses. However, the increase in DHEA, due to its anabolic condition, could counteract their effect, suggesting a positive effect on their professional actions.
由于需要做出决策，医院急诊室的卫生专业人员的工作压力非常大。在本研究中，我们考虑评估急诊卫生工作者的应激反应，在整个工作日测量相关生物标志物，如皮质醇、脱氢表雄酮（DHEA）和唾液α-淀粉酶。
进行了一项分析性、描述性和横断面研究。该研究在两家公立医院的急诊室进行。97 名专业人员参与了研究，其中 45 名来自一家医院，52 名来自另一家医院。根据昼夜节律，共采集了 4 份唾液样本：8:00、12:00、15:00 和 24:00 h/24 h。随后对数据进行了分析。
皮质醇水平在整个工作日内逐渐下降，24 h 时达到最低值。DHEA 也呈现出类似的模式。α-淀粉酶水平在整个工作日内逐渐升高，在 15:00 h 时达到峰值，而在 24 h 时则低于其他工作日的数据。
由于未呈现参考/基线值，因此这项工作重点关注急诊室在没有极端情况的一个正常工作日期间经历的应激情况。在这种情况下，通过皮质醇和α-淀粉酶测量的应激存在于急诊室医生和护士中。然而，DHEA 的增加，由于其合成代谢状态，可能会抵消其影响，表明其对专业行动有积极影响。
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