Gavrilovici Cristina, Spoială Elena-Lia, Ivanov Anca-Viorica, Mocanu Adriana, Ștreangă Violeta, Alecsa Mirabela-Smaranda, Miron Ingrith
Pediatrics Department, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.
Healthcare (Basel). 2021 Apr 14;9(4):458. doi: 10.3390/healthcare9040458.
Otitis media (OM) represents a public health matter, being the main cause of preventable hearing loss in pediatric patients. Besides well-established risk factors for developing OM, such as craniofacial abnormalities, prematurity, low birth weight, or tobacco exposure, there is evidence that obesity could be associated with a high incidence of OM. Our aim is to perform a literature review on the state of current published research on the relationship between OM and obesity and to discuss the interconnectivity between these two entities. We conducted an electronic search in PubMed and EMBASE databases. Out of 176 references, 15 articles were included in our study. Our findings suggest that obesity and overweight might be risk factors for developing OM, and vice versa. The main mechanisms for developing OM in obese patients include alteration in cytokine profile, increased gastroesophageal reflux, and/or fat accumulation. Conversely, ear infections exposure might increase the risk of obesity, mostly by taste changes through middle ear cavity inflammation.
中耳炎（OM）是一个公共卫生问题，是小儿患者可预防听力损失的主要原因。除了已明确的中耳炎发病风险因素，如颅面异常、早产、低出生体重或接触烟草外，有证据表明肥胖可能与中耳炎的高发病率有关。我们的目的是对目前已发表的关于中耳炎与肥胖关系的研究状况进行文献综述，并讨论这两个实体之间的相互联系。我们在PubMed和EMBASE数据库中进行了电子检索。在176篇参考文献中，有篇文章纳入了我们的研究。我们的研究结果表明，肥胖和超重可能是发生中耳炎的风险因素，反之亦然。肥胖患者发生中耳炎的主要机制包括细胞因子谱改变、胃食管反流增加和/或脂肪堆积。相反，耳部感染可能会增加肥胖风险，主要是通过中耳腔炎症引起味觉改变。
