Carbone Manuel Glauco, Campo Giovanni, Papaleo Enrico, Marazziti Donatella, Maremmani Icro
PISA-School of Experimental and Clinical Psychiatry, 56100 Pisa, Italy.
Department of Medicine and Surgery, Division of Psychiatry, University of Insubria, 21100 Varese, Italy.
J Clin Med. 2021 Apr 10;10(8):1616. doi: 10.3390/jcm10081616.
Endometriosis is a chronic inflammatory condition, which is distinguished by the presence of the endometrial-like glands and stroma outside the uterine cavity. Pain and infertility are the most commonly expressed symptoms, occurring in 60% and 40% of cases, respectively. Women with endometriosis, especially those with pelvic pain, also have a greater vulnerability to several psychiatric disorders. There is, in particular, a tendency to contract affective or anxiety disorders as well as panic-agoraphobic and substance use disorders. Endometriosis with pelvic pain, infertility and psychic vulnerability usually leads to disability and a markedly lower quality of life for women of reproductive age. Thus, the burden of endometriosis is not limited to the symptoms and dysfunctions of the disease; it extends to the social, working and emotional spheres, leading to a severe impairment of global functioning. An analysis of scientific literature revealed a close relationship between specific temperamental traits, the expression of several psychiatric symptoms, chronicity of pain, risk of substance use and lower probability of a positive outcome. Endometriosis symptoms and the impact of related psychological consequences, increased vulnerability and the possible onset of psychiatric symptoms may influence coping strategies and weaken resilience, so triggering a vicious cycle leading to a marked deterioration in the quality of life. A multidisciplinary approach consisting of a medical team composed of gynecologists, psychologists, psychiatrists, experts in Dual Disorder, algologists and sexologists, would guarantee the setting of a target and taking the best decision on a personalized treatment plan. That approach would allow the prompt detection of any psychopathological symptoms and improve the endometriosis-related physical symptoms, bringing a healthier quality of life and a greater likelihood of a positive outcome.
子宫内膜异位症是一种慢性炎症性疾病,其特征是子宫腔外存在类似子宫内膜的腺体和间质。疼痛和不孕是最常见的症状,分别发生在60%和40%的病例中。患有子宫内膜异位症的女性,尤其是那些有盆腔疼痛的女性,也更容易患几种精神疾病。特别是,她们有患情感或焦虑障碍以及惊恐-广场恐惧症和物质使用障碍的倾向。伴有盆腔疼痛、不孕和心理易损性的子宫内膜异位症通常会导致残疾,并使育龄女性的生活质量显著下降。因此,子宫内膜异位症的负担不仅限于该疾病的症状和功能障碍;它还延伸到社会、工作和情感领域,导致整体功能严重受损。对科学文献的分析揭示了特定气质特征、几种精神症状的表达、疼痛的慢性程度、物质使用风险与积极结果可能性较低之间的密切关系。子宫内膜异位症的症状以及相关心理后果的影响、易损性增加和精神症状的可能发作可能会影响应对策略并削弱恢复力,从而引发恶性循环,导致生活质量明显恶化。由妇科医生、心理学家、精神科医生、双相障碍专家、疼痛专家和性学家组成的医疗团队采用多学科方法,将确保设定目标并就个性化治疗方案做出最佳决策。这种方法将能够迅速发现任何精神病理症状,并改善与子宫内膜异位症相关的身体症状,带来更健康的生活质量和更大的积极结果可能性。