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由短期肾脏病学经验医生进行肾活检的安全性。

Safety of Renal Biopsy by Physicians with Short Nephrology Experience.

作者信息

Torigoe Kenta, Muta Kumiko, Tsuji Kiyokazu, Yamashita Ayuko, Abe Shinichi, Ota Yuki, Mukae Hiroshi, Nishino Tomoya

机构信息

Department of Nephrology, Nagasaki University Hospital, Nagasaki 852-8501, Japan.

Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.

出版信息

Healthcare (Basel). 2021 Apr 16;9(4):474. doi: 10.3390/healthcare9040474.

DOI:10.3390/healthcare9040474
PMID:33923650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8072574/
Abstract

Percutaneous renal biopsy is an essential tool for diagnosing various renal diseases; however, little is known about whether renal biopsy performed by physicians with short nephrology experience is safe in Japan. This study included 238 patients who underwent percutaneous renal biopsy between April 2017 and September 2020. We retrospectively analyzed the frequency of post-renal biopsy complications (hemoglobin decrease of ≥10%, hypotension, blood transfusion, renal artery embolization, nephrectomy and death) and compared their incidence among physicians with varied experience in nephrology. After renal biopsy, a hemoglobin decrease of ≥10%, hypotension and transfusion occurred in 13.1%, 3.8% and 0.8% of patients, respectively. There were no cases of post-biopsy renal artery embolism, nephrectomy, or death. The composite complication rate was 16.0%. The incidence of post-biopsy complications was similar between physicians with ≥3 years and <3 years of clinical nephrology experience (12.5% vs. 16.8%, = 0.64). Furthermore, the post-biopsy composite complication rates were similar between physicians with ≥6 months and <6 months of clinical nephrology experience (16.3% vs. 15.6%, > 0.99). Under attending nephrologist supervision, a physician with short clinical nephrology experience can safely perform renal biopsy.

摘要

经皮肾活检是诊断各种肾脏疾病的重要手段;然而,在日本,对于肾病经验不足的医生进行肾活检是否安全,人们知之甚少。本研究纳入了2017年4月至2020年9月期间接受经皮肾活检的238例患者。我们回顾性分析了肾活检后并发症(血红蛋白下降≥10%、低血压、输血、肾动脉栓塞、肾切除术和死亡)的发生频率,并比较了不同肾病经验医生之间的发生率。肾活检后,分别有13.1%、3.8%和0.8%的患者出现血红蛋白下降≥10%、低血压和输血情况。没有活检后肾动脉栓塞、肾切除术或死亡的病例。复合并发症发生率为16.0%。临床肾病经验≥3年和<3年的医生之间,活检后并发症的发生率相似(12.5%对16.8%,P = 0.64)。此外,临床肾病经验≥6个月和<6个月的医生之间,活检后复合并发症发生率相似(16.3%对15.6%,P>0.99)。在肾科主治医生的监督下,临床肾病经验不足的医生可以安全地进行肾活检。

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本文引用的文献

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A nationwide survey on clinical practice patterns and bleeding complications of percutaneous native kidney biopsy in Japan.一项针对日本经皮肾活检临床实践模式和出血并发症的全国性调查。
Clin Exp Nephrol. 2020 May;24(5):389-401. doi: 10.1007/s10157-020-01869-w. Epub 2020 Mar 18.
2
Risk Factors Associated with Major Complications after Ultrasound-Guided Percutaneous Renal Biopsy of Native Kidneys.超声引导下经皮肾活检术后发生主要并发症的相关危险因素。
Kidney Blood Press Res. 2020;45(1):122-130. doi: 10.1159/000504544. Epub 2019 Dec 10.
3
How to Successfully Train a Modern Nephrologist: Experience from US Fellowship Training Practice.如何成功培养一名现代肾脏病学家:来自美国专科培训实践的经验
Kidney Dis (Basel). 2019 Oct;5(4):204-210. doi: 10.1159/000502976. Epub 2019 Sep 17.
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Update on the Native Kidney Biopsy: Core Curriculum 2019.更新后的原发性肾脏活检:2019 年核心课程。
Am J Kidney Dis. 2019 Mar;73(3):404-415. doi: 10.1053/j.ajkd.2018.10.011. Epub 2019 Jan 17.
5
Changing Trends in the Performance of Percutaneous Renal Biopsy from Nephrologist to Interventional Radiologist: A Single-Center Experience.经肾内科医生到介入放射科医生行经皮肾活检术操作表现的变化趋势:单中心经验。
Am J Nephrol. 2018;48(5):326-329. doi: 10.1159/000493925. Epub 2018 Oct 24.
6
Comparison of native and transplant kidney biopsies: diagnostic yield and complications.自体肾活检与移植肾活检的比较:诊断率及并发症
Clin Kidney J. 2018 Oct;11(5):616-622. doi: 10.1093/ckj/sfy051. Epub 2018 Jul 6.
7
Risk of percutaneous renal biopsy of native kidneys in the evaluation of acute kidney injury.在急性肾损伤评估中对天然肾脏进行经皮肾活检的风险。
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8
Safety and adequacy of percutaneous kidney biopsy performed by nephrology trainees.肾内科实习生进行经皮肾活检的安全性和充分性。
BMC Nephrol. 2018 Jan 15;19(1):14. doi: 10.1186/s12882-017-0796-y.
9
Risk factors for bleeding complications after nephrologist-performed native renal biopsy.肾脏科医生进行的自体肾活检后出血并发症的危险因素。
Clin Kidney J. 2017 Aug;10(4):573-577. doi: 10.1093/ckj/sfx012. Epub 2017 Mar 15.
10
Interventional nephrology: current status and clinical impact in Japan.介入肾脏病学:日本的现状与临床影响
Clin Exp Nephrol. 2018 Apr;22(2):437-447. doi: 10.1007/s10157-017-1457-y. Epub 2017 Aug 2.