School of Instrument Science and Opto-Electronics Engineering, Hefei University of Technology, Hefei 230009, China.
Sensors (Basel). 2021 Apr 13;21(8):2721. doi: 10.3390/s21082721.
Microscopic imaging is of great significance for medical diagnosis. However, due to the strong scattering and absorption of tissue, the implementation of non-invasive microscopic imaging is very difficult. Traditional single-pixel microscopes, based on reflective optical systems, provide an alternative solution for scattering media imaging. Here, the single-pixel microscope with transmissive liquid crystal modulation is proposed. The microscopic ability of the proposed microscope is calibrated. The multi-spectral microscopic imaging of the object is demonstrated. The transmissive imaging of the object behind the scattering media is analyzed. The proposed prototype of the transmissive single-pixel microscope is expected to be applied in microscopic imaging through scattering media and medical imaging.
微观成像是医学诊断的重要手段。然而,由于组织的强散射和强吸收,实现非侵入式微观成像是非常困难的。传统的基于反射光学系统的单像素显微镜为散射介质成像提供了一种替代解决方案。在这里,提出了一种基于透射液晶调制的单像素显微镜。对所提出的显微镜的微观能力进行了校准。演示了物体的多光谱微观成像。分析了散射介质后面的物体的透射成像。所提出的透射单像素显微镜原型有望应用于散射介质中的微观成像和医学成像。