Department of Radiology, Pennsylvania State University, Hershey, PA 17033, USA.
Vagelos College of Physicians and Surgeons (VP&S), Columbia University, New York, NY 10032, USA.
Tomography. 2021 Apr 13;7(2):120-129. doi: 10.3390/tomography7020011.
Accurate measurement of object volumes using computed tomography is often important but can be challenging, especially for finely convoluted objects with severe marginal blurring from volume averaging. We aimed to test the accuracy of a simple method for volumetry by constructing, scanning and analyzing a phantom object with these characteristics which consisted of a cluster of small lucite beads embedded in petroleum jelly. Our method involves drawing simple regions of interest containing the entirety of the object and a portion of the surrounding material and using its density, along with the densities of pure lucite and petroleum jelly and the slice thickness to calculate the volume of the object in each slice. Comparison of our results with the object's true volume showed the technique to be highly accurate, irrespective of slice thickness, image noise, reconstruction planes, spatial resolution and variations in regions of interest. We conclude that the method can be easily used for accurate volumetry in clinical and research scans without the need for specialized volumetry computer programs.
使用计算机断层扫描准确测量物体体积通常很重要，但具有挑战性，特别是对于具有严重边缘模糊的精细卷积物体，因为其体积会被平均化。我们旨在通过构建、扫描和分析具有这些特征的幻影物体来测试一种简单体积测量方法的准确性，该物体由嵌入凡士林中的一簇小有机玻璃珠组成。我们的方法涉及绘制简单的感兴趣区域，包含物体的全部和一部分周围材料，并使用其密度，以及纯有机玻璃和凡士林的密度以及切片厚度来计算每个切片中物体的体积。我们的结果与物体的真实体积进行比较，结果表明该技术无论切片厚度、图像噪声、重建平面、空间分辨率和感兴趣区域的变化如何，都具有高度的准确性。我们得出结论，该方法可以在临床和研究扫描中轻松用于准确的体积测量，而无需专门的体积测量计算机程序。
